BACKGROUND Zinc supplementation decreases morbidity from infections and increases growth of stunted children, but there is little information on functional responses to zinc delivered in fortified foods. OBJECTIVE The aim was to examine the effects of zinc fortification on the growth, morbidity from infections, and plasma zinc concentrations of young children. DESIGN We compared the physica...

Although iron and zinc deficiencies are known to occur together and also appear to be high in Ghana, a few supplementation studies addressed this concurrently in pregnancy. In a double-blind, randomized controlled trial, 600 pregnant women in Ghana were randomly assigned to receive either a combined supplement of 40 mg of zinc as zinc gluconate and 40 mg of iron as ferrous sulphate or 40 mg of ...

introduction: zinc has been known as an essential trace element in human, animal and plant nutrition. during pregnancy, the daily requirement increases to 25% and its serum level decreases. the serum level of zinc in adults is arranged from 80 to 150 μg/dl. considering the importance of this trace element and its role during pregnancy, this study was conducted on pregnant women in the community...

A bioassay for zinc status in humans has been sought due to the importance of zinc, an essential trace metal, for many divergent functions in the human body; however, a sensitive bioassay for zinc status in humans is lacking. To address this issue, we established gene expression profiles of human lymphoblastoid cells treated with 0 or 30 micro mol/L ZnSO(4) using microarray technology. A limite...

Dietary zinc intakes, selected biochemical indices of zinc status, and milk zinc concentrations were determined at monthly intervals throughout lactation for 53 middle-income lactating women, 14 of whom received a daily supplement of 15 mg zinc. Overall mean dietary zinc intake for the non-supplemented group (NZS) was 10.7 ± 4.1 mg/day ( ± SD). The mean dietary zinc intake of the zinc supplemen...

Objective(s) Clinicians have long been searching for ways to obtain "super normal" wound healing. Zinc supplementation improves the healing of open wounds. Honey can improve the wound healing with its antibacterial properties. Giving supplemental zinc to normal rats can increase the wound tensile strength. This work is to study the concurrent effects of zinc and honey in wound healing of norma...

BACKGROUND People with kidney failure are often deficient in zinc and selenium, but little is known about the optimal way to correct such deficiency. METHODS We did a double-blind randomized trial evaluating the effects of zinc (Zn), selenium (Se) and vitamin E added to the standard oral renal vitamin supplement (B and C vitamins) among hemodialysis patients in Alberta, Canada. We evaluated t...

Obesity often leads to obesity-related cardiac hypertrophy (ORCH), which is suppressed by zinc-induced inactivation of p38 mitogen-activated protein kinase (p38 MAPK). In this study, we investigated the mechanisms by which zinc inactivates p38 MAPK to prevent ORCH. Mice (4-week old) were fed either high fat diet (HFD, 60% kcal fat) or normal diet (ND, 10% kcal fat) containing variable amounts o...

OBJECTIVE To evaluate whether zinc supplementation during pregnancy is associated with an increase in birth weight. DESIGN A randomized double-blind placebo-controlled trial. SETTING Outpatient clinic and delivery service at the University of Alabama at Birmingham. PATIENTS Five hundred eighty medically indigent but otherwise healthy African-American pregnant women with plasma zinc levels...