: The reactivated form of the varicella-zoster virus (VZV) is responsible for chickenpox, known as herpes zoster (HZ). Although it a self-limiting infection, presents debilitating and painful mucosal dermal vesicular eruptions. Early identification management are vital to curbing spread HZ infection. In this extensive review, we present an overview HZ, including its structure, pathophysiology, ...

Reactivation of latent Varicella-Zoster virus may cause various neurological complications including meningitis, encephalitis, myelitis, vasculopathy resulting in stroke and pseudotumor cerebri. It occurs mainly in elderly or immunocompromised patients and is very rare in children. We report a 4-year and 6-months old immunocompetent boy who developed encephalitis and cerebellites, due to reacti...

Colleagues—Varicella-zoster virus (VZV) has been recognized as one of the most frequent viral opportunistic infections in patients infected with the human immunodeficiency virus (HIV). The classic presentation of VZV infection in patients with AIDS is a multidermatomal zoster with or without dissemination. Persistent VZV infections with atypical cutaneous lesions have been recognized with incre...

BACKGROUND Because experimental acute retinal necrosis (ARN) induced by herpes simplex virus in mice develops only if mice fail to acquire virus-specific delayed hypersensitivity (DH), although they produce antiviral antibodies (ie, anterior chamber-associated immune deviation), we sought to determine whether a similar inverse correlation exists for patients with varicella-zoster virus (VZV)-in...

Analysis of saliva samples from individuals aged ≥ 60 years who had a history of zoster (group 1), zoster and postherpetic neuralgia (PHN; group 2), or no history of zoster (group 3) revealed varicella zoster virus (VZV) DNA in saliva samples from 11 of 17 individuals in group 1, 10 of 15 individuals in group 2, and 2 of 17 individuals in group 3. The frequency of VZV DNA detection was signific...

Varicella-zoster virus (VZV) infection is restricted to humans, which hinders studies of its pathogenesis in rodent models of disease. To facilitate the study of VZV skin tropism, we developed an ex vivo system using human fetal skin organ culture (SOC). VZV replication was analyzed by plaque assay, transmission electron microscopy, and histology. The yield of infectious VZV from SOC increased ...

Herpes zoster (HZ) is caused by the reactivation of varicella-zoster virus (VZV), which has ability to remain latent in neural tissue. We report a case rare complication, abdominal pseudohernia, developed 63-year-old woman, partial protrusion wall due paralysis muscles.

Varicella-zoster virus (VZV) is a ubiquitous human alphaherpesvirus that causes varicella (chicken pox) and herpes zoster (shingles). Varicella is a common childhood illness, characterized by fever, viremia, and scattered vesicular lesions of the skin. As is characteristic of the alphaherpesviruses, VZV establishes latency in cells of the dorsal root ganglia. Herpes zoster, caused by VZV reacti...


 Disseminated varicella-zoster virus (VZV) infection has devastating impacts on patients’ quality of life, with increasing morbidity and mortality. Thus, it is imperative that a diagnosis be made early. This case description illustrates unique dramatic presentation disseminated VZV important clinical implications.

Definition Varicella-zoster virus (VZV), also known as Human Herpes Virus III (HHVIII), is a member of the herpes virus group. As all the other viruses from this group, VZV can manifests itself as a recurrent infection. After entering the body and causing primary infection, varicella-zoster virus remains latent in the neurons of sensory ganglion, especially dorsal roots of ganglion of the spina...