A study by Keam et al demonstrated that influenza vaccination, regardless of timing during 3-week cytotoxic chemotherapy cycles, may provide seroprotection. The majority of patients in this study were women with either breast or lung cancer. In an earlier study of patients with colorectal cancer, influenza vaccination was found to result in fewer cases of influenza, fewer cases of pneumonia, an...

Amelioration of cardiovascular risk through a high intake of dietary fibre was originally highlighted by Ancel Keys and colleagues in the Journal of Nutrition in 1960 (Keys et al. 1960). More than 45 years later there is a growing body of evidence supporting the association between intake of whole grains and decreased incidence of fatal and nonfatal CHD (Liu et al. 1999; Steffen et al. 2003; Je...

In order to evaluate the ability of multivalent glycosides based on a beta-cyclodextrin core as site-specific molecular carriers, a study on both the inclusion complexation behaviour and lectin binding affinity of branched and hyperbranched beta-cyclodextrins is presented. A series of cluster galactosides constructed on beta-cyclodextrin scaffolds containing seven 1-thio-beta-lactose or beta-la...

Amphiphilic cyclodextrin–fullerene conjugates have potential biological activity, due to their water solubility. In order to study the influence of the linker of these conjugates on solubility and aggregation, a permethylated β-cyclodextrin–C60 conjugate with a short linker –(CH2)2NHCO–, which is attached to the secondary face of β-cyclodextrin was synthesized. Its solubility in water and its U...

The complex [Ru(bpy)2L] , where bpy = 2,2’-bipyridine, L = 4-(phenylethynyl)-2,2’-bipyridine, was prepared in its racemic and resolved forms (and . The phenylethynyl unit on the bipyridine for the complex acts as a binding site for -cyclodextrin in water (1:1 complex, K = 3390 M) or -cyclodextrin (2:1 complex, K1 = 887 M , K2 = 8070 M ). The presence of the cyclodextrin provides partial p...

Abstract Micropollutants are persistent and hazardous materials in low concentrations (ng L −1 –μg ), including substances such as pharmaceuticals, personal care products industrial chemicals. The advancement of analytical chemistry has allowed for the detection micropollutants; however, an efficient economical treatment solution is yet to be installed. Fungal laccase been a successful biocatal...

Multifunctional nanocomposites Ag/Al2O3/TiO2@β-cyclodextrin-graphene oxide (AATG) incorporating graphene sheets, TiO2, and Ag/Al2O3 nanoparticles were prepared in two steps. We benefited from the inherent properties of β-cyclodextrin to create a stable aqueous solution capable self-assembling situ grown TiO2 on nanosheets. catalysts with high surface-to-volume ratio by combustion technique urea...

A green chiral lab-on-a-chip cyclodextrin-based microchip electrophoretic method was developed for enantioseparation of baclofen (BCN) and phenylalanine (Phe) enantiomers the first time. All BCN Phe were offline labeled with 4-fluoro-7-nitrobenzofurazan (NBD-F) or fluorescein-5-isothiocyanate (FITC) fluorogenic reagents prior to microfluidic injection in a dynamically coated polymethylmethacryl...

In healthy older subjects, the glycaemic response to carbohydrate-containing meals is dependent on gastric emptying and intestinal absorption; when the latter is slowed, the magnitude of the rise in glucose is attenuated. The oligosaccharide a-cyclodextrin has been reported to diminish the glycaemic response to starch in young adults; this effect has been attributed to the inhibition of pancrea...

In healthy older subjects, the glycaemic response to carbohydrate-containing meals is dependent on gastric emptying and intestinal absorption; when the latter is slowed, the magnitude of the rise in glucose is attenuated. The oligosaccharide α-cyclodextrin has been reported to diminish the glycaemic response to starch in young adults; this effect has been attributed to the inhibition of pancrea...