Human chorionic gonadotropin (hCG) is produced primarily by differentiated syncytiotrophoblasts, and represents a key embryonic signal that is essential for the maintenance of pregnancy. hCG can activate various signaling cascades including mothers against decapentaplegic homolog 2 (Smad2), protein kinase C (PKC), and/or protein kinase A (PKA) in several cells types by binding to luteinizing ho...

Introduction The early diagnosis of ectopic pregnancy, made before the occurrence of complications linked to an hemodinamic instability, leads to a reduction of mortality from 35.5. to 3.8 per 1000 ectopic pregnancies .When the diagnosis is made, there are different therapeutic options that depend on the conditions of the patient, the β-hCG levels, the dimension of the adnexal mass, the conditi...

This review describes briefly the beneficial use of two vaccines developed by us for treatment of cancers. The vaccine against Luteinizing Hormone Releasing Hormone (LHRH) is effective in carcinoma of prostate as well as in breast cancers dependent on androgens and estrogens respectively. LHRH being identical in both males and females, the same vaccine is usable in both Prostate and Breast ster...

OBJECTIVES The objective was to examine associations of neonatal weight gain (NWG) and head circumference gain (HCG) with IQ scores and behavior at early school age. METHODS We used data from the Promotion of Breastfeeding Intervention Trial, involving Belarusian infants born full term and weighing ≥2500 g. NWG and HCG were measured as the percentage gain in weight and head circumference over...

This is a report of a case of cornual ectopic pregnancy, with transvaginal ultrasonography done for early detection, screening, β-hCG measuring, also discussed was the role of methotrexate therapy prior to operative procedure with conservative management. Multiple intramural myomas (22 myomas) in this case were strongly believed as the etiology of the cornual pregnancy. (Med J Indones 2008; 18:...

1. Department of Radiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Mailing address: Richard C. Semelka, MD. UNC Department of Radiology. 101 Manning Drive CB#7510 – 2001 Old Clinic Bldg. Chapel Hill, NC 27599-7510, USA. E-mail: [email protected]. destruens is a locally invasive (myometrium) manifestation of complete HM that represents 13% of cases of GTD. Two perce...