background: cell therapy of many neurodegenerative diseases using bone marrow stromal cells (bmsc) requires the differentiation of bmsc into neuronal subtype. however, the transdifferentiation of bmsc into gabaergic phenotype requires more investigation. methods: in this study, bmsc of adult female rats were pre-induced into neuroblast-like cells using 1 mm β-mercaptoethanol (βme) and 10 m ret...

A “Indústria Têxtil”, empresa familiar com mais de 40 anos atividade, tinha suas decisões centralizadas e tomadas pelo presidente. Com a expansão dos negócios, houve divizionalização atrelada à criação uma controladoria implantação da Gestão Baseada em Valor (GBV). Em dois GBV implantada, o lucro econômico foi sucessivamente gerado, mas volume vendas mostrou-se diminuindo constantemente. Diante...

This study aimed at evaluating the response to supplementation of β-Mannanase with two levels energy on performance, carcass yield, and meat quality 1600 1-d-old straight run Indian River broilers which were randomly allotted 4 dietary treatments (10 replicates/treatment, 40 chicks per replicate) in a 35-d feeding trial. The trial consisted 2 phases, starter (0 14 d) grower (15 35 d). experimen...

Triterpenoids have been used for medicinal purposes in many Asian countries because of their anti-inflammatory, antioxidant, antiproliferative, anticancer, and anticarcinogenic properties. Bardoxolone methyl, the C-28 methyl ester of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid (CDDO) known as CDDO-Me or RTA 402, is one of the derivatives of synthetic triterpenoids. CDDO-Me has been used for th...

In this study, the methanolic extract (ME) and essential oil (EO) of medicinal plant Artemisia campestris L. were investigated for their antioxidant activity antifungal efficacy on postharvest storage decays; Botrytis cinerea Pers. Penicillium expansum Link. The total polyphenolic flavonoid contents determined. ME had higher (400.64 µg GAE/mg 43.13 ± 0.14 μg QE/mg, respectively) than EO (27.47 ...

discussion of the many faces of relativism occupies a highly prominent place in the epistemological literature. protagoras in ancient greece and nelson goodman in the modern period are two most notable proponent of relativism. in the present article, i discuss and explain relativistic approaches of this two important relativist. i will first briefly define and review some faces of relativism. t...

background: many efforts have been undertaken until now to find an alternative approach to packed red cell tranfusion in major β-thalassemia. augmentation of fetal hemoglobin by hydroxyurea has proved to be less effective in this condition as compared to sickle cell anemia, probably due to molecular heterogeneity of the former disease. hydroxyurea efficacy and its relation to xmn1 polymorphism ...

background: mutations in β -globin gene may result in β-thalassemia major, which is one of the most common genetic dis­or­ders in iran and some other countries. knowing the beta-globin mutation spectrum improves the efficiency of prenatal diagno­sis in the affected fetuses (major β-thalassemia) of heterozygote couples. methods: couples with high hemoglobin a 2 and low mean corpuscular volume we...