UNLABELLED WHAT IS KNOWN ON THE SUBJECT?: Novel psychoactive substances (NPS) include synthetic drugs mimicking the effects of illicit drugs, e.g. synthetic cannabinoids, and herbs such as Salvia divinorum. NPS are substances that can trigger hallucinations and other effects altering the mind, and are currently uncontrolled by the United Nations' 1961 Narcotic Drugs/1971 Psychotropic Substances...

during the past few years, there has been an increasing recognition that internet is playing a significant role in the synthesis, the distribution and the consumption of novel psychoactive substances (nps).the aim of this study was to assess the online availability of nps in persian language websites.the google search engine was used to carry out an accurate qualitative assessment of informatio...

In this paper, we report the first time preparation of SnO2 nanoparticles (NPs) using a green chemistry method. The leaf extract of Plectranthus amboinicus was used as reducing and stabilization agent for synthesizing SnO2 NPs. The synthesized SnO2 NPs were characterized by SEM, EDX, XRD and UV-vis spectroscopy. Results showed that the biosynthesized SnO2 NPs owing a high purity. The photocatal...

The toxicity of CuO nanoparticles (CuO NPs) to human hepatocarcinoma (HepG2) cells was investigated in this study. CuO NPs (1 40 mg/L) had significant toxicity to HepG2 cells. The antioxidant N-acetyl-L-cysteine (NAC) significantly reduces the cytotoxicity induced by the CuO NPs, supporting the hypothesis that oxidative stress contributes to the cytotoxicity of CuO NPs. To further explore the o...

OBJECTIVE To examine role transition and support requirements for nurse practitioner (NP) graduates in their first year of practice from the perspectives of the NPs and coparticipants familiar with the NPs' practices; and to make recommendations for practice, education, and policy. DESIGN Descriptive qualitative design informed by focused ethnography and narrative analysis using semistructure...

The temporal-spatial interaction of land cover and non-point source (NPS) nutrient pollution were analyzed with the Soil and Water Assessment Tool (SWAT) to simulate the temporal-spatial features of NPS nutrient loading in the upper stream of the Yellow River catchment. The corresponding land cover data variance was expressed by the normalized difference vegetation index (NDVI) that was calcula...

23 Amygdala plasticity is an important contributor to the emotional-affective dimension of 24 pain. Recently discovered neuropeptide S (NPS) has anxiolytic properties through 25 actions in the amygdala. Behavioral data also suggest antinociceptive effects of centrally 26 acting NPS, but site and mechanism of action remain to be determined. This is the first 27 electrophysiological analysis of p...

Tacrolimus (FK506), an effective immunosuppressant for treating inflammatory skin diseases, hardly penetrates into and through the skin owing to its high hydrophobicity and molecular weight. The aim of this study was to develop a hybrid system based on nicotinamide (NIC) and nanoparticles (NPs) encapsulating FK506, such as FK506-NPs-NIC, for facilitating percutaneous delivery, which exploited v...

Octahedral,cuboctahedral,branched and ‘rice-like’Pt NPs were synthesised using a seed-mediated growth route. Pt NPs (3 nm) were prepared and dispersed in oleyl amine to form a seed solution and then Pt(acac)2 was added. By adjusting the molar ratio of Pt from Pt(acac)2 and seed NPs, the seed diameter and the addition route of Pt(acac)2, the NPs growth could be controlled to fall into in a kinet...

MPd (M = Co, or Cu) nanoparticles (NPs) were synthesized by borane-amine reduction of metal acetylacetonates. The size of the MPd NPs was controlled at 3.5 nm and their compositions were tuned by the molar ratios of the metal precursors. These MPd NPs were active catalysts for electrochemical oxidation of formic acid and the Cu30Pd70 NPs showed the highest mass activity at 1192.9 A gPd(-1), muc...