BACKGROUND An elevated (201)Tl lung uptake after stress is related to an adverse prognosis. METHODS AND RESULTS The functional and prognostic significance of resting (201)Tl lung uptake was assessed in 124 consecutive patients with ischemic heart disease and ejection fraction </=35% undergoing rest-redistribution tomography to evaluate myocardial viability. (201)Tl lung uptake significantly c...

Introduction: Thallium-201 (Tl-201) is routinely administered to people undergoing nuclear medicine scans at activity levels of 3-5 milli curies (mCi). Due to its short halflife, relatively low hazard radiations and rapid biological excretion, thallium-201 has very low radio toxicity when introduced internally. However, the recommended dose of Tl-201 is considered clinical safe and gets excrete...

Background Diffuse myocardial fibrosis (MF) in dilated cardiomyopathy (DCM) is closely related to systolic and diastolic cardiac failure and could be identified as a major independent value prediciting clinical outcome. It results from elevated levels of collagen and is therefore associated with an expansion of the extracellular volume (ECV). Up to now, the detection of MF requires myocardial b...

This study was undertaken to examine the ability of SPECT in differentiation of a pulmonary lesion suspecions of lung cancr. A total of 170 patients with suspected lung cancer were studied. A dose of Tl-201 chloride {148-296 MBq) was injected intravenously and tomographic early and delayed scans were obtained at 15 miniutes and 3 hours post injection, respectively. Delayed Tl-201 SPECT vi...

PURPOSE To differentiate radiation necrosis from tumor recurrence using single-photon emission CT (SPECT). METHODS Forty-two thallium-201 SPECT scans were obtained in 33 adult patients. All patients had previously been treated with either conventional external-beam radiation therapy (XRT) (26 patients) or gamma knife radiosurgery (16 patients) and had subsequent contrast-enhanced MR examinati...

Thallium-201 myocardial scintigraphy was performed in patients with congenital heart defects to determine whether, by quantification of right ventricular isotope uptake, one could assess the degree of right ventricular hypertrophy and so predict the level of right ventricular pressure. A total of 24 patients ranging in age from 7 months to 30 years was studied; 18 were studied before corrective...