We show that forms of Bayesian and MDL inference that are often applied to classification problems can be inconsistent. This means there exists a learning problem such that for all amounts of data the generalization errors of the MDL classifier and the Bayes classifier relative to the Bayesian posterior both remain bounded away from the smallest achievable generalization error.

We propose a new inductive principle, which we call the complexity approximation principle (CAP). This principle is a natural generalization of Rissanen’s minimum description length (MDL) principle and Wallace’s minimum message length (MML) principle and is based on the notion of predictive complexity, a recent generalization of Kolmogorov complexity. Like the MDL principle, CAP can be regarded...

This paper proposes a new regularization method based on the MDL (Minimum Description Length) principle. An adequate precision weight vector is trained by approximately truncating the maximum likelihood weight vector. The main advantage of the proposed regularizer over existing ones is that it automatically determines a regularization factor without assuming any specific prior distribution with...

OBJECTIVE Adenylyl cyclases (ACs) play important role in regulating pancreatic beta cell growth, survival and secretion through the synthesis of cyclic AMP (cAMP). MDL-12,330A and SQ 22536 are two AC inhibitors used widely to establish the role of ACs. The goal of this study was to examine the effects of MDL-12,330A and SQ 22536 on insulin secretion and underlying mechanisms. METHODS Patch-cl...

BACKGROUND AND PURPOSE Stroke patients often experience a significant temporal delay between the onset of ischemia and the time to initiation of therapy. Thus, there is a need for neuroprotectants with a long therapeutic window of opportunity. The efficacy of a potent, central nervous system-penetrating calpain inhibitor (MDL 28,170) was evaluated in a temporary model of focal cerebral ischemia...

Polyamine oxidase functions in the polyamine catabolic pathway, converting N1-acetyl-spermidine and -spermine into putrescine (Put) and spermidine (Spd), respectively, thereby facilitating homeostasis of intracellular polyamine pools. Inhibition of polyamine oxidase in hematopoietic cells by a specific inhibitor, N,N'-bis(2,3-butadienyl)-1,4-butanediamine (MDL-72,527), reduces the levels of Put...

Due to Covid-19 pandemic, schools, particularly in the rural areas employed Modular Distance Learning (MDL) ensure education continuity. This study seeks investigate effects of MDL academic performance learners whether there is a significant difference their before and after implementation MDL. Mixed method was applied this study; Quantitative using T-Test compare GWA Qualitative through use se...

We give sound and complete Hilbert-style axiomatizations for propositional dependence logic (PD), modal dependence logic (MDL), and extended modal dependence logic (EMDL) by extending existing axiomatizations for propositional logic and modal logic. In addition, we give novel labeled tableau calculi for PD, MDL, and EMDL. We prove soundness, completeness and termination for each of the labeled ...