Directed energy deposition (DED) has matured into an essential additive manufacturing (AM) branch. DED been broadly implemented in the design and fabrication of novel materials. These include metals, ceramics, composites. Successful operation requires a good understanding many critical phenomena, including laser-material interactions, fundamentals casting solidification alloys, welding metallur...

Microstructure design allows to prevent intergranular cracking and premature failure in Co–Ni–Ga shape memory alloys. Favorable grain boundary configurations are established using additive manufacturing techniques, namely, direct energy deposition (DED) laser powder bed fusion (L-PBF). L-PBF establish a columnar structure. In the alloy processed by DED, microstructure with strong ⟨001⟩ texture ...

To examine clinical management and prescribing patterns for dry eye disease (DED), in relation to severity subtype, by care practitioners across the globe. An online, anonymous cross-sectional survey (on Qualtrics) translated into 14 languages was distributed The included six questions around of DED, subtype. completed 1139 eyecare professionals (37% ophthalmologists 58% optometrists) from 51 c...

To assess the six-month therapeutic profiles of lipid and non-lipid-based artificial tear supplements in managing dry eye disease (DED). Ninety-nine participants fulfilling TFOS DEWS II diagnostic criteria for DED (64% females; mean ± SD age, 44 16 years) were enrolled a prospective, multicentre, double-masked, parallel group, randomised controlled trial. Participants instilled lipid-based nano...

A particle’s motion in crowded environments often exhibits anomalous diffusion, whose nature depends on the situation at hand and is formalized within different physical models. Thus, such environments may contain traps, labyrinthine paths or macromolecular structures, which the particles may be attached to. Physical assumptions are translated into mathematical models which often come with nice...

This paper proposes a new model for multi-area dynamic economic dispatch (MA-DED) problem, taking into account hydro-thermal generating units, wind power generation and power pool market, for supplying the overall demand of the system for a given horizon. The uncertainties in wind power generations, energy prices and demand of the system are also modeled to make the proposed approach more pract...

Abstract Purpose To assess the association between dry eye disease (DED) and alcohol consumption using a large population-based cohort. Methods 77,145 participants (19–94 years, 59% female) from Dutch Lifelines cohort were cross-sectionally assessed for DED Women's Health Study (WHS) questionnaire. Alcohol intake was self-reported food frequency questionnaires. The relationship use analyzed log...

•Reproxalap was superior to vehicle for the symptoms and signs of dry eye disease.•No significant changes in safety measures were observed reproxalap groups.•Reactive aldehyde species (RASP) inhibition may be a promising therapy disease. PurposeTo assess activity reproxalap, novel reactive inhibitor, relative patients with disease (DED)DesignRandomized, double-masked, vehicle-controlled Phase 2...