BACKGROUND Oxidized low-density lipoprotein (LDL) is associated with cardiovascular disease. Macrophages contribute to LDL oxidation, and oxidized LDL (oxLDL) affects macrophage function. We searched for the strongest gene correlates of oxLDL in macrophages in coronary plaques and studied the effect of oxLDL on their expression in THP-1 cells. METHODS AND RESULTS Gene expression in macrophage...

Saccades aimed at spatially extended targets land reliably at central locations determined by pooling information across the target shape [Melcher, D., & Kowler, E. (1999). Shape, surfaces and saccades. Vision Research, 39, 2929-2946; Vishwanath, D., & Kowler, E. (2003). Localization of shapes: Eye movements and perception compared. Vision Research, 43, 1637-1653]. Previous findings of saccadic...

BACKGROUND In observational studies, clinical outcomes for black patients with coronary disease have been worse than for white patients. There are few data from randomized trials comparing the outcomes of coronary revascularization between black patients and white patients. METHODS AND RESULTS We analyzed data from the Bypass Angioplasty Revascularization Investigation randomized trial. At st...

1. W. J. Eckert, "The computation of special perturbations by the punched card method," Astronomical Jn., v. 44, 1935, p. 177-182. 2. W. J. Eckert, Dirk Brouwer, & G. M. Clémence, "Coordinates of the five outer planets (1653-2060)," Astronomical papers prepared for the use of the American Ephemeris and Nautical Almanac, v. 12, U. S. Gov. Printing Office, Washington, D. C, 1951. 3. Dirk Brouwer,...

OBJECTIVE To quantify and characterise the reports of syncope and seizures following quadrivalent (4v) human papillomavirus (HPV) vaccination. DESIGN AND SETTING Retrospective case series of notifications to SAEFVIC (Surveillance of Adverse Events Following Vaccination In the Community), May 2007 - April 2009. MAIN OUTCOME MEASURES Incidence of syncope and seizure following 4vHPV vaccinatio...

The back-calculation technique for evaluating the anthropogenic CO2 (CANT) input corrects total inorganic carbon for the remineralization of organic matter and the dissolution of calcium carbonate, along with subtracting the pre-industrial equilibrium total inorganic carbon. This technique is mainly dependent on the estimation of the preformed values of total alkalinity, oxygen and partial pres...

Chickpea (Cicer arietinum L.) is an important crop legume plant with high nutritional value. The transcriptomes of desi and wild chickpea have already been sequenced. In this study, we sequenced the transcriptome of kabuli chickpea, C. arietinum (genotype ICCV2), having higher commercial value, using GS-FLX Roche 454 and Illumina technologies. The assemblies of both Roche 454 and Illumina datas...

effects of different planting on phenology, grain yield and its components of two sunflower culitvars were investigated. in 1996, an experiment was conducted in the experimental field of azad islamic university of khorasgan, located in khatonabad village, isfahan. the experiment was arranged in a randomized complete block design with a split plot layaout and four replications. the main plots co...