We demonstrate that, in an appropriate limit, the off-shell M5-brane worldvolume action effectively captures the scalar potential of Seiberg-Witten theory perturbed by a small super-potential and, consequently, any nonsupersymmetric vacua that it describes. This happens in a similar manner to the emergence from M5's of the scalar potential describing certain type IIB flux configurations [1]. We...

We investigated the subtype of presynaptic muscarinic receptors associated with inhibition of acetylcholine (ACh) release in the mouse small intestine. We measured endogenous ACh released from longitudinal muscle with myenteric plexus (LMMP) preparations obtained from M1-M5 receptor knockout (KO) mice. Electrical field stimulation (EFS) increased ACh release in all LMMP preparations obtained fr...

Recently, noncommutative theories have received renewed interest, after it was found that noncommutative theories can be naturally realized in M theory compactified in the presence of constant three-form field background @1# and within string theories as the worldvolume theory of a D-brane with a nonzero constant Neveu-Schwarz ~NS! B field @2,3#. In the case of a D-brane with a constant magneti...

Motivated by Sen's spacetime prescription for the construction of theories with self-dual field strengths, we present a rigid superspace Lagrangian describing noninteracting tensor multiplets living on stack M5-branes and containing all physical constraints fields, yielding on-shell matching degrees freedom. The geometric approach adopted here offers natural realization superdiffeomorphisms is ...

Diverse muscarinic allosteric ligands exhibit greatest affinity toward the M2 receptor subtype and lowest affinity toward M5. In this study, we evaluated the potencies with which two groups of highly M2/M5 selective allosteric agents modulate the dissociation of [3H]N-methylscopolamine from M2/M5 chimeric and point-mutated receptors. These allosteric ligands included two alkane-bisammonium comp...