the use of bacteriocins, mainly nisin, is one of the most significant preservation technologies in the food industry. nisin encapsulation can improve stability and homogenous distribution in food matrices. in this study, liposomes of four various lipids (lipoid s 100, lipoid s pc-3, lipoid s pc, and lipoid pc (dppc)) were prepared by dehydration-rehydration method, and compared for entrapment e...

Abstract Frequent loss of heterozygosity (LOH) on the short arm human chromosome 3 (3p) region has been found in pancreatic cancer (PC), which suggests likely presence tumor suppressor genes this region. However, functional significance LOH development PC not clearly defined. The telomerase reverse transcriptase gene ( hTERT) contributes to unlimited proliferative and tumorigenicity malignant t...

Real-time distributed system speciication and veriication in asynchronous propositional temporal logic. Let A be the integrator system deened in Figure 5. We use the xpoint computation procedure to prove that the formula y 60 ! 20t y is an invariant of A. It follows that the gas burner leaks at most one twentieth of the time in any interval of at least 60 seconds. Let R i = hpc = 1 ^ t = 0 ^ x ...

BACKGROUND The results of prostate specific antigen (PSA) and digital rectal examination (DRE) screenings lead to both under and over treatment of prostate cancer (PCa). As such, there is an urgent need for the identification and evaluation of new markers for early diagnosis and disease prognosis. Studies have shown a link between PCa, lipids and lipid metabolism. Therefore, the aim of this stu...

Introduction: Purkinje Cell (PC) output displays a complex firing pattern consisting of high frequency sodium spikes and low frequency calcium spikes, and disruption in this firing behavior may contribute to cerebellar ataxia. Riluzole, neuroprotective agent, has been demonstrated to have neuroprotective effects in cerebellar ataxia. Here, the spectral analysis of PCs firing in control, 3-acety...

Recently microRNAs (miRNAs) have been attractive targets with their key roles in biological regulation through post-transcription to control mRNA stability and protein translation. Though melatonin was known as an anti-angiogenic agent, the underlying mechanism of melatonin in PC-3 prostate cancer cells under hypoxia still remains unclear. Thus, in the current study, we elucidated the important...

PSM-E is a newly discovered alternatively spliced variant of prostate-specific membrane antigen (PSMA). In the current study, its role on the proliferation, invasiveness and migration in prostate cancer cell lines was analyzed. PSM-E and PSMA (as a comparison) eukaryotic expression vectors pcDNA3.0/PSM-E and pcDNA3.0/PSMA were constructed, validat...

BACKGROUND Statins have recently been studied for their proapoptotic and antimetastatic effects. However, the exact mechanisms of their anticancer actions remain unclear. Using microarrays, we discovered up-regulation of annexin A10 (ANXA10) in PC-3 cells after simvastatin treatment. ANXA10 reportedly has antitumor effects. In this study, we evaluated the effects of simvastatin on ANXA10 signal...

The role of ATP-sensitive potassium (K(ATP)) channels in the late phase of ischemic preconditioning (PC) remains unclear. Furthermore, it is unknown whether K(ATP) channels serve as end effectors both for late PC against infarction and against stunning. Thus, in phase I of this study, conscious rabbits underwent a 30-min coronary occlusion (O) followed by 72 h of reperfusion (R) with or without...