The aim of this study was to examine the effect of crude bile on the human HepG2 and CCRF-CEM cell lines. Cells were exposed to different dilutions of bile. Antiproliferative effects were determined by the cytotoxic MTT assay. Cells undergoing apoptosis were identified by terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay. Bile administration resulted in dose-dependent c...

We propose a general approach for estimating the parameters of latent variable probability models to maximize conditional likelihood and discriminant criteria. Unlike joint likelihood, these objectives are better suited for classiication and regression. The approach utilizes and extends the previously introduced CEM framework (Conditional Expectation Maximization), which reformulates EM to hand...

It is demonstrated how all the mechanical equations of classical electrodynamics (CEM) may be derived from only Coulomb's inverse square force law, special rel-ativity and Hamilton's Principle. The instantaneous nature of the Coulomb force in the centre-of-mass frame of two interacting charged objects, mediated by the exchange of space-like virtual photons, is predicted by QED. The interaction ...

It is demonstrated how all the mechanical equations of classical electrodynamics (CEM) may be derived from only Coulomb's inverse square force law, special rel-ativity and Hamilton's Principle. The instantaneous nature of the Coulomb force in the centre-of-mass frame of two interacting charged objects, mediated by the exchange of space-like virtual photons, is predicted by QED. The interaction ...

It is demonstrated how all the mechanical equations of classical electrodynamics (CEM) may be derived from only Coulomb's inverse square force law, special rel-ativity and Hamilton's Principle. The instantaneous nature of the Coulomb force in the centre-of-mass frame of two interacting charged objects, mediated by the exchange of space-like virtual photons, is predicted by QED. The interaction ...

It is demonstrated how all the mechanical equations of Classical Electromag-netism (CEM) may be derived from only Coulomb's inverse square force law, special relativity and Hamilton's Principle. The instantaneous nature of the Coulomb force in the centre-of-mass frame of two interacting charged objects, mediated by the exchange of space-like virtual photons, is predicted by QED. The interaction...