Rabbit and cow anti-Streptococcus dysgalactiae sera were tested by bacterial agglutination, complement fixation, hemagglutination, and immunodiffusion for the presence of antibody. The results of these tests were compared with mouse-protection studies on the same serum to estimate which in vitro test would best reflect the in vivo protective capacity of serum. Identification of the antibody con...

An indirect hemagglutination (IHA) test and a complement fixation (CF) test were evaluated from test results on sera from 212 human melioidosis patients of which 119 were culturally proved cases. Significant antibody titers (IHA titers of 1:40 or greater and CF titers of 1:4 or greater) were demonstrated with either test in all except five patients. IHA and CF titers ranged as high as 1:20,480 ...

The literature concerning various serological reactions in malaria in man has been well reviewed (1). According tothis review, attempts to obtain a specific complement fixation reaction with sera from human beings infected by Plasmodium vivax or by Plasmodium falciparum have led in the past to inconclusive results because no sensitive, specific, and easily standardized antigen was available. Du...

Taylor-Robinson, David (National Institutes of Health, Bethesda, Md.), Norman L. Somerson, Horace C. Turner, and Robert M. Chanock. Serological relationships among human mycoplasmas as shown by complement-fixation and gel diffusion. J. Bacteriol. 85:1261-1273. 1963.-Antigenic relationships among human mycoplasmas were studied by complement-fixation and agar gel diffusion techniques. Four recogn...

Parent bacteria and L-forms of some streptococci of group A, group D, and Streptococcus MG share common antigens as shown by cross-reactivity in growth inhibition, complement fixation, and Ouchterlony tests. Cross-reactivity between these streptococci or their L-forms with a staphylococcal L-form, or Mycoplasma pneumoniae, was found only rarely and only in low-titer complement fixation tests. R...

The serological diagnosis of virus infections depends for the most part on neutralization and complement fixation tests. Both of these have been described in the case of herpes simplex infections, but the neutralization test is used almost exclusively at present, owing to the conflicting results obtained by complement fixation. The reports in the literature on this subject are at variance with ...

The complement fixation elution profiles of dengue-2 virus-infected suckling mouse brain supernatant fluids from Sephadex G-200 columns were compared by the antigen end-point titration procedure and by a complement dilution technique. The latter technique was found to be a quick method for approximating the complement-fixing antigen in eluates.

7S sheep antibody is similar to 7S rabbit antibody, insofar as it too can be digested with pepsin to yield a 5S fragment still capable of precipitating homologous antigen. The 5S fragment from rabbit as well as sheep antibody is capable of fixing guinea pig complement. However, this fixation differs from the fixation by 7S antibody, since preformed antibody-antigen aggregates containing either ...

....................................................................................................................................7 POPULÄRVETENSKAPLIG SAMMANFATTNING...................................................................9 LIST OF PAPERS........................................................................................................................ 11 MY CONTRIBUTIONS TO IN...

Hapten-antibody complexes prepared at equivalence with the bivalent hapten bis-DNP-octamethylene-diamine and purified rabbit anti-DNP antibody were fractionated by Sepharose gel-filtration and the fractions examined by electron microscopy. Individual fractions were tested for whole-complement fixation and C1 fixation. Dimer forms did not show this type of biological activity, while fractions co...