This paper revisits the classical inference results for profile quasi maximum likelihood estimators (profile MLE) in the semiparametric estimation problem. We mainly focus on two prominent theorems: the Wilks phenomenon and Fisher expansion for the profile MLE are stated in a new fashion allowing finite samples and model misspecification. The method of study is also essentially different from t...

The current study aims at determining the antioxidant properties of Morus alba leaves extract (MLE) on various organs of mice. Forty male Swiss albino mice were divided into control group and three different groups which received three different doses of MLE orally for 10 days. The glutathione, nitrite/nitrate, malondialdehyde levels were estimated in kidney, testis, spleen and jejunum of adult...

The focus is on the approximation of solution BSDE in case where forward equation observed presence small Gaussian noise. volatility considered to depend some unknown parameter. This made several steps. First a preliminary estimator obtained, then using Kalman-Bucy filtration equations and Fisher-score device one-step MLE-process this parameter constructed. approximated by means PDE One-step ML...

Objectives: Bone marrow-derived mesenchymal stem cells (BMSCs) are considered to have potential clinical application value in the treatment of acute lung injury (ALI). Myeloid-derived growth factor (MYDGF) can promote proliferation cell. We hypothesized that MYDGF may play a role reducing vitro and vivo through bone marrow cells. Methods: An model lipopolysaccharide (LPS)(MLE-12) was establishe...

Here, we present a method that can improve the z-tracking accuracy of the recently invented TSUNAMI (Tracking of Single particles Using Nonlinear And Multiplexed Illumination) microscope. This method utilizes a maximum likelihood estimator (MLE) to determine the particle's 3D position that maximizes the likelihood of the observed time-correlated photon count distribution. Our Monte Carlo simula...

We consider a wide-band ad-hoc network with coherent radios in a slow-fading environment, and we analyze the performance of different physical layer (PHY) and medium access (MAC) schemes in such a network. Most of the existing analysis assume that PHY is based on a nearest neighborhood decoding, which is not optimal in this case. Instead, we focus on MLE detector. We show that, since some of th...

We study nonparametric estimation for current status data with competing risks. Our main interest is in the nonparametric maximum likelihood estimator (MLE), and for comparison we also consider a simpler “naive estimator.” Groeneboom, Maathuis and Wellner [Ann. Statist. (2008) 36 1031– 1063] proved that both types of estimators converge globally and locally at rate n1/3. We use these results to...

The acute toxicity of mango leaves extract (MLE) at the maximal dose (18.4 g/kg) was studied in ICR mice and no abnormalities were detected during the experiment. The long-term studies at various doses of MLE (100 mg/kg, 300 mg/kg, and 900 mg/kg) in SD rats for 3 consecutive months revealed that, compared with the control group, rats in MLE treated groups showed slight body weight increase and ...

Objectives. To clarify the difference between Lyapunov exponents (LEs) for cleft palate (CP) patients with hypernasality versus without hypernasality and to investigate the relationship between their LEs and nasalance scores (NSs). Material and Methods. Six CP patients with severe hypernasality (mean age 9.2 years) and six CP patients without hypernasality (mean age 8.0 years) were enrolled. Fi...