Background The A2A adenosine receptor is a prototypical G proteincoupled receptor. It is expressed in a wide variety of cells including as different types as neurons, platelets, cells of the immune system and muscle. The cell-specific expression of the A2A adenosine receptor is controlled by at least three different upstream non-coding exons and their corresponding promotors. Compared to other ...

The goal of the FID/LD Workshop on Linguistics and Information Science was to contribute to the development of a comprehensive plan that can be used to guide research activities for more effective use of linguistics in information science. To appreciate our progress toward that goal during the.three days at Biskops-Arno in May of 1976, it is necessary to consider in some detail the stimulus tha...

Two approaches toward the arrow of time for scattering processes have been proposed in rigged Hilbert space quantum mechanics. One, due to Arno Bohm, involves preparations and registrations in laboratory operations and results in two semigroups oriented in the forward direction of time. The other, employed by the Brussels-Austin group, is more general, involving excitations and de-excitations o...

Sec7-related guanine nucleotide exchange factors (GEFs) initiate vesicle budding from the Golgi membrane surface by converting the GTPase ARF to a GTP-bound, membrane-associated form. Here we report the crystal structure of the catalytic Sec7 homology domain of Arno, a human GEF for ARF1, determined at 2.2 angstroms resolution. The Sec7 domain is an elongated, all-helical protein with a distinc...

Anne Conrad, Amo Herzig, Franklin Kopitzsch (Hrsgg.), Das Volk im Visier der Aufklärung. Studien zur Popularisierung Aufklärung späten 18. Jahrhundert (Veröffentlichungen des Hamburger Arbeitskreises für Regionalgeschichte, Bd. 1), Hamburg (LIT Verlag) 1998. 266 S.