INTRODUCTION Telehealth has been widely promoted as a technology to make healthcare more effective and affordable. However, current telehealth systems suffer from vendor lock-in and high cost, and are designed for managing chronic diseases rather than preventing them. METHODS We address shortcomings of existing consumer-level health informatics applications in supporting senior health consume...

Introduction BioSense 2.0, a redesigned national syndromic surveillance system, provides users with timely regional and national data classified into disease syndromes, with views of health outcomes and trends for use in situational awareness. As of July 2014, there are 60 jurisdictions nationwide feeding data into BioSense 2.0. In New Jersey, the state’s syndromic surveillance system, EpiCente...

(S)-Hydroxymandelate synthase (Hms) is a nonheme Fe(II) dependent dioxygenase that catalyzes the oxidation of 4-hydroxyphenylpyruvate to (S)-4-hydroxymandelate by molecular oxygen. In this work, the substrate promiscuity of Hms is characterized in order to assess its potential for the biosynthesis of chiral α-hydroxy acids. Enzyme kinetic analyses, the characterization of product spectra, quant...

UNLABELLED BACKGROUND The aim of the paper is to assess by the principal components analysis (PCA) the heavy metal contamination of soil and vegetables widely used as food for people who live in areas contaminated by heavy metals (HMs) due to long-lasting mining activities. This chemometric technique allowed us to select the best model for determining the risk of HMs on the food chain as wel...

Hybrid male sterility (HMS) is a rapidly evolving mechanism of reproductive isolation in Drosophila. Here we report a genetic analysis of HMS in third-chromosome segments of Drosophila mauritiana that were introgressed into a D. simulans background. Qualitative genetic mapping was used to localize 10 loci on 3R and a quantitative trait locus (QTL) procedure (multiple-interval mapping) was used ...

Future manufacturing systems will be required to be agile, flexible, and fault-tolerant. Next generation manufacturing systems will be integrated networks of distributed resources simultaneously capable of combined knowledge processing and material processing. The objective of this research is to define a generic open architecture for such kind of distributed manufacturing systems, especially f...

Citation: Al-Anazi KA (2017) Molecular Diagnostics Moving Hematological Malignancies into the Era 0f Precision Medicine. J Mol Genet Med Vol.1 No.1:5 Cancer is a genomic disorder resulting from cellular accumulation of genetic alterations [1]. The first complete cancer genome, obtained from a patient with acute myeloid leukemia (AML), was reported in the year 2008 [2]. Hematopoiesis requires se...