In view of previous studies demonstrating a significant correlation between adenosine triphosphate (ATP) depletion and impairment of chemotaxis (CTX) during granulocyte (PMN) storage, we sought to quantitate the relationship between CTX and PMN energy metabolism. We incubated PMNs at 37 degrees C with 2-deoxyglucose (2-dg) in the presence of 5 mmol/L glucose. As expected, ATP inhibition by 2-dg...

To better understand encoding and decoding of stimulus information in two specific hippocampal sub-regions, we isolated and co-cultured rat primary dentate gyrus (DG) and CA3 neurons within a two-chamber device with axonal connectivity via micro-tunnels. We tested the hypothesis that, in these engineered networks, decoding performance of stimulus site information would be more accurate when sti...

There is a considerable amount of work in the scientific literature on nonlinear (“paradoxical”) effects, but their toxicological significance for body still poorly understood. Plant growth regulators are biologically active substances at level low and ultra-low doses concentrations, they widely used agriculture. To date, mechanisms toxic specific effects body, presence “paradoxical” have not b...

This work describes the construction of a sensitive, stable, and label-free sensor based on a dual-gate field-effect transistor (DG FET), in which uniformly distributed and size-controlled silicon nanowire (SiNW) arrays by nanoimprint lithography act as conductor channels. Compared to previous DG FETs with a planar-type silicon channel layer, the constructed SiNW DG FETs exhibited superior elec...

Brominated poly(dG-dC) . poly(dG-dC), which forms a stable Z-DNA helix under physiological salt conditions, was used as an antigen to produce monoclonal antibodies from mice. The anti-Z-DNA antibodies were specific for the Z conformation as was shown by direct binding studies and a competitive solid phase assay. Competition could only be seen by brominated poly(dG-dC) . poly(dG-dC) under low an...

Recently, Yekutieli introduced projective dimension, injective dimension and flat of DG-modules by generalizing the characterization ordinary modules vanishing Ext or Tor-groups. In this paper, we introduce a DG-version projective, resolution for over connective DG-algebra which are different from known resolutions. An important feature these resolutions is that, roughly speaking, “length” give...

introduction: this report describes the synthesis of 2-amino-2-deoxy(s-benzoylthioacetyl)-d-glucose (s-bz-ta-dg), radiolabeled with [99mtc(co)3(oh2)3]+ complex with a procedure including deprotection of the benzoyl group, characterization by hplc using a c18 reverse phase column and preliminary biodistribution study in normal mice. methods: [99mtc(co)3(h2o)3]+ complex was used to label ta-dg w...

Commentary What is the dentate gyrus (DG) good for? The answer may depend on whether or not you are interested in learning and memory, or epilepsy. While the actual circuitry is more complicated, the DG is the initial relay in the hippocampal circuit from the entorhinal cortex (EC). From there the DG projects to hippocampal sub-region Cornu Ammonis 3 (CA3), CA3 projects to hippocampal sub-regio...