Objective To determine whether the same relationships between early-life risk factors and socioeconomic status (SES) with childhood body mass index (BMI) are observed in a modern cohort (2000) compared historic (1947). Study design The SES BMI were examined 2 prospective birth cohorts from region, born 50 years apart: 711 children 1947 Newcastle Thousand Families Study (NTFS) ...

This study develops an end-to-end deep learning framework to learn and analyze ground motions (GMs) through their latent features, achieve reliable GM classification, selection, generation of simulated motions. The is composed analysis workflow that transforms reconstructs GMs short-time Fourier transform (STFT), encodes decodes features convolutional variational autoencoder (CVAE), classifies ...

Abstract This study used GMS-Modflow to investigate the ten-year groundwater potential in Concepcion, Tarlac. region Central Luzon, Philippines, with limited surface water, depends on as its primary freshwater source. The water demand projection estimated an increase of 38.5% from 2020 2030; hence, higher abstraction is perceived next ten years. To deviate risk associated reliance groundwater, ...

The objective of the current study was to formulate solid lipid nanoparticles of oxybenzone to enhance its sunscreening efficacy while reducing its side effects. Solid lipid nanoparticles (SLNs) of oxybenzone were prepared by the solvent diffusion method. A complete 2(4) factorial design was used to optimize preparations. The study design involves the investigation of four independent variables...

Clinical outcome after traumatic diffuse axonal injury (DAI) is difficult to predict. In this study, three magnetic resonance imaging (MRI) sequences were used to quantify the anatomical distribution of lesions, to grade DAI according to the Adams grading system, and to evaluate the value of lesion localization in combination with clinical prognostic factors to improve outcome prediction. Thirt...

The aim of this paper, written by the committee of educational research methodology of the "Society for Medical Education" of the German-speaking countries, will give recommendations for the review process of scientific papers in medical education. The recommendations are based on the results of a workshop in 2007 and on a survey among reviewers of the journal GMS Z Med Ausbild. It reflects on ...

Members of the immunity-related GTPase (IRG) family are interferon-inducible resistance factors against a broad spectrum of intracellular pathogens including Toxoplasma gondii. The molecular mechanisms governing the function and regulation of the IRG resistance system are largely unknown. We find that IRG proteins function in a system of direct, nucleotide-dependent regulatory interactions betw...

PURPOSE OF REVIEW This article reviews the evidence linking gut bacteria, endotoxin, and its circulating levels with inflammatory induced obesity and metabolic disease (metabolic endotoxaemia). RECENT FINDINGS Gut flora analyses have allowed gut microbiota signatures (GMS) to be observed in animal studies of obesity/metabolic disease. In these studies, specific GMS result in a change in obesi...

The qualitative assessment of general movements (GMs) has been shown to be a better predictor of neurological outcome than the traditional neurological examination in brain-damaged preterm infants. The aim of this study was to compare the results of the two techniques in term infants. Off-line assessment of GMs from videorecordings and neurological examinations were carried out, from birth till...