Genome-wide systematic screens in yeast have uncovered a large gene network (the telomere length maintenance network or TLM), encompassing more than 400 genes, which acts coordinatively to maintain telomere length. Identifying the genes was an important first stage; the next challenge is to decipher their mechanism of action and to organize then into functional groups or pathways. Here we prese...

In recent years, transaction level modeling (TLM) has enabled designers to simulate complex embedded systems and SoCs, orders of magnitude faster than simulation at the RTL. The increasing complexity of the systems on one hand, and availability of low cost parallel processing resources on the other hand have motivated the development of parallel simulation environments for TLMs. The existing si...

With increasing number of IP cores, parallel communication architectures including NoCs have emerged for many-core systems. To efficiently architect NoCs, early analysis of crucial run-time metrics such as throughput, latency and saturation time is required. This requires abstract modeling of NoCs. Modeling abstraction, and consequently the modeling granularity impacts the accuracy and speed of...

Today's systems on chip (SoCs) require a complex design and verification process. In early stages, high-level debugging of the SoC functionality is feasible TLM (Transaction-Level Modeling) descriptions. To ease such SoC's models, Assertion-Based Verification (ABV) enables runtime temporal properties. last RTL (Register Transfer Level) descriptions hardware blocks expose microarchitectural deta...

The emergence of data-intensive applications, such as Deep Neural Networks (DNN), exacerbates the well-known memory bottleneck in computer systems and demands early attention design flow. Electronic System-Level (ESL) using SystemC Transaction Level Modeling (TLM) enables effective performance estimation, space exploration, gradual refinement. However, contention is often only detectable after ...

Dual scattering channel schemes extend the transmission line matrix numerical method (Johns’ TLM algorithm) in two directions. For one point, transmission line links are replaced by abstract scattering channels in terms of paired distributions (characteristic impedances are thus neither needed, nor in general defined, e.g.). In the second place, non-trivial cell interface scattering is admitted...

The procedure for analysis of electromagnetic field in a cylindrical metallic cavity, based on reflection and transmission characteristic, is presented in the paper. An analysis of procedure efficiency to resonant modes identification is conducted numerically and experimentally verified. As a numerical tool, TLM time-domain method, enhanced with the compact wire model to account for the presenc...

Dual scattering channel schemes extend the transmission line matrix numerical method (Johns’ TLM algorithm) in two directions. For one point, transmission line links are replaced by abstract scattering channels in terms of paired distributions (characteristic impedances are thus neither needed, nor in general defined, e.g.). In the second place, non-trivial cell interface scattering is admitted...

In this paper, circuital and numerical models of metal enclosure with apertures are considered for the purpose of accurate shielding effectiveness calculation. An improved circuital model is presented to account for the presence of receiving dipole antenna which is often used in practice to measure the level of electromagnetic field at selected points inside the enclosure. Receiving antenna of ...

Boron is a plant nutrient essential for adequate plant growth, yet the range between B deficiency and toxicity levels is rather narrow. Boron adsorption reactions with soil components, particularly sesquioxides, most often regulate the amount of B in the soil solution. The reaction mechanisms of B adsorption on oxides have not been fully characterized, however. Pressure-jump relaxation experime...