Aerosol optical depth (AOD), an important indicator of atmospheric aerosol load, characterizes the impacts on radiation balance and turbidity. The nesting Elterman model a spatiotemporal linear mixed-effects (ST-LME) model, which is referred to as ST-Elterman retrieval (ST-ERM), was employed improve temporal resolution AOD prediction. This produces daily in Southern Central Hebei Plain (SCHP) r...

While studying the functions of CCM3/PDCD10, a gene encoding an adaptor protein whose mutation results in vascular malformations, we have found that it is involved in a novel response to oxidative stress that results in phosphorylation and activation of the ezrin/radixin/moesin (ERM) family of proteins. This phosphorylation protects cells from accidental cell death induced by oxidative stress. ...

in epithelial integrity, polarity, and junction formation was suggested for the Drosophila ERM ortholog Dmoesin, which was proposed to act by antagonizing rho signaling rather than by providing a structural function (Polesello et al., 2002; Speck et al., 2003). A role of ERM Verena Göbel,1,* Peter L. Barrett,1 David H. Hall,2 and John T. Fleming1 Laboratory of Developmental Immunology Massachus...

Alterations in the erm(A) regulatory region of six clinical isolates of Staphylococcus epidermidis and one of Staphylococcus haemolyticus displaying a constitutive resistance phenotype were investigated. Anovel deletion of 10 bp with respect to the corresponding sequence of Tn554 was identified in the attenuator of a constitutively expressed erm(A) gene of one of the S. epidermidis isolates. Th...

ERM (Ezrin, Radixin, Moesin) proteins are membrane-cytoskeleton linkers that regulate the structure and the function of specific domains of the plasma membrane. ERM proteins are expressed in all metazoan analyzed so far. Genetic analysis of ERM protein functions has recently been performed simultaneously in three different organisms, mouse, Drosophila melanogaster and C. elegans. These studies ...

adherens junctions — within the apical junctional region of the Drosophila embryonic epithelium; this may provide mechanical stability during the junctional remodeling that accompanies tissue morphogenesis. Too much or too little ERM-mediated crosslinking impairs the migration of mesendoderm cells during zebrafish gastrulation and homing lymphocytes in mice. This is due in part to the cells’ in...

Erythromycin and tylosin are commonly used in animal production, and such use is perceived to contribute to the overall antimicrobial resistance (AR) reservoirs. Quantitative measurements of this type of AR reservoir in microbial communities are required to understand AR ecology (e.g., emergence, persistence, and dissemination). We report here the development, validation, and use of six real-ti...

The ERM family is composed of the proteins ezrin, moesin and radixin, which are cell structure-related proteins. Despite the detection of viable roles of ERM family proteins, the impact of these molecules in cancer pathogenesis has yet to be investigated. Evidence emerging from clinical and translational studies showed that the ERM family is linked to disease progression in clinical cancers. We...

Members of the Mycobacterium abscessus group (MAG) cause lung, soft tissue, and disseminated infections. The oral macrolides clarithromycin and azithromycin are commonly used for treatment. MAG can display clarithromycin resistance through the inducible erm(41) gene or via acquired mutations in the rrl (23S rRNA) gene. Strains harboring a truncation or a T28C substitution in erm(41) lose the in...