نتایج جستجو برای: ژن gd
تعداد نتایج: 26404 فیلتر نتایج به سال:
Graves' disease (GD) is a common thyroid disease, and Graves ophthalmopathy(GO) is the most common extra-thyroidal manifestation of GD. Genetic associations of the thyroid stimulating hormone receptor (TSHR) gene with GD and GO have been studied in different population groups for a long time. We aimed to obtain a more precise estimation of the effects of TSHR single nucleotide polymorphisms (SN...
Graves' disease (GD) is a leading cause of hyperthyroidism, which affects 1.0-1.6% of the general population. Previous studies reported a higher GD prevalence in Asian populations compared to Caucasian populations. The etiology of GD involves complex interactions between predisposing genes and environmental triggers. Genetic studies have shown that the human leukocyte antigen (HLA) is an import...
The ability of chelated Gd to serve as an effective magnetic resonance (MR) contrast agent largely depends on fast exchange rates between the Gd-bound water molecules and the surrounding bulk water. Because water diffuses slowly across lipid bilayers, liposomes with encapsulated chelated Gd have not been widely adopted as MR contrast agents. To overcome this limitation, we have synthesized chem...
Graves' disease (GD) is one of the most common endocrine diseases. Antithyroid drugs (ATDs) treatment is frequently used as the first-choice therapy for GD patients in most countries due to the superiority in safety and tolerance. However, GD patients treated with ATD have a relatively high recurrence rate after drug withdrawal, which is a main limitation for ATD treatment. It is of great impor...
OBJECTIVES/HYPOTHESIS Graves' disease (GD) has multiple adverse effects on the cardiovascular system. We aimed to examine the outcome of thyroidectomy in patients with cardiac manifestations of GD and evaluate their associated postoperative complications. STUDY DESIGN Retrospective analysis using a prospectively collected database. METHODS A retrospective analysis of our prospectively colle...
The hallmark of neuronopathic Gaucher disease (GD) is oculomotor abnormalities, but ophthalmological assessment is difficult in uncooperative patients. Chromatic pupillometry is a quantitative method to assess the pupillary light reflex (PLR) with minimal patient cooperation. Thus, we investigated whether chromatic pupillometry could be useful for neurological evaluations in GD. In our neuronop...
A randomized double-blind crossover comparison of 0.2 mmolikg Gd-DTPA and 0.1 mmolikg Gd-BOPTA was performed in 25 patients for MRA of the aorta and sopra aortic trunk, and the renal, mesenteric, lumbar, iliac and femoral arteries. Blinded qualitative evaluation by two radiologists revealed no differences in terms of lesion size, signal intensity or degree of stenosis. The results indicate that...
The identification of parental inbred lines to develop superior hybrids is a rather costly and time-consuming step in maize breeding. In some cases, pedigree information has been used to select diverse parental lines. In the case of Iranian maize inbred lines, this information is not fully available. In this study we investigated the genetic distance (GD) based on Simple sequence Repeats (SSR) ...
The coexistence of Crohn’s disease (CD) and autoimmune thyroid diseases [Graves’ disease (GD) and Hashimoto’s thyroiditis (HT)] is uncommon, although these conditions involve autoimmune processes. This report reviews the English and Japanese literature, including proceedings regarding coexisting CD and the autoimmune thyroid diseases GD and HT, and discusses cases of concomitant CD and GD (six ...
An evaluation was done of the effect of gadolinium diethylenetriaminepentaacetic acid (DTPA) on computed tomographic (CT) studies performed after magnetic resonance (MR) imaging. CT scans of two solutions of Gd-DTPA demonstrated substantial attenuation. In two patients who underwent CT after Gd-DTPA-enhanced MR imaging, the high attenuation of concentrated Gd-DTPA was seen in the urinary bladde...
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