نتایج جستجو برای: ژن rhob

تعداد نتایج: 16213  

Journal: :Biomedicine & Pharmacotherapy 2021

The Ras homolog (Rho) family of small GTPases comprise several proteins with prominent roles in regulation cell cycle transition, migration, and remodeling actin cytoskeleton. Expression these is regulated by factors among them are long non-coding RNAs (lncRNAs). impact lncRNAs on Rho signaling can be exerted through direct modulation expression or influencing miRNAs that negatively regulate GT...

Journal: :Transactions of the Iron and Steel Institute of Japan 1979

2015
Bunsoon Choi Hyoun-Ah Kim Chang-Hee Suh Hae Ok Byun Ju-Yang Jung Seonghyang Sohn

The purpose of this study was to clarify the correlation between microRNA-21 (miR-21) expression and inflammation in a herpes simplex virus (HSV)-induced Behçet's Disease (BD) mouse model. miR-21 was compared between BD patients and healthy controls in peripheral blood mononuclear cells (PBMC). For miR-21 inhibition, miR-21 antagomir was applied to BD mice. The change of symptoms was monitored....

2015
Julia R Pon Jackson Wong Saeed Saberi Olivia Alder Michelle Moksa S-W Grace Cheng Gregg B Morin Pamela A Hoodless Martin Hirst Marco A Marra

Myocyte enhancer factor 2B (MEF2B) is a transcription factor with mutation hotspots at K4, Y69 and D83 in diffuse large B-cell lymphoma (DLBCL). To provide insight into the regulatory network of MEF2B, in this study, we analyse global gene expression and DNA-binding patterns. We find that candidate MEF2B direct target genes include RHOB, RHOD, CDH13, ITGA5 and CAV1, and that indirect target gen...

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