OBJECTIVE To evaluate the effect of comorbidity and other risk factors on postoperative mortality and morbidity in patients undergoing major oesophageal and gastric surgery. DESIGN Multicentre cohort study with data on postoperative mortality and morbidity in hospital. DATA SOURCE AND METHODS The ASCOT prospective database, comprising 2087 patients with newly diagnosed oesophageal and gastr...

Objective: In this study, knowledge, attitude and behaviors of university students on organ donation were investigated. Material and Method: A stratified random sample of 955 students were asked for six sociodemographic, seven personal information, nine behavior and twenty attitude questions using a Likert-type scale survey form. Results: Totally 955 students participated the study and 85.6% re...

Background: The Script Concordance (SC) approach was used as an alternative test format to measure the presence of knowledge organization reflective in one’s clinical reasoning skills (i.e., diagnostic, investigation and treatment knowledge). Method: We investigated the reliability and validity of a 40-item paediatric version of the SC test with three groups representing 53 medical students (no...

Rev Esp Cardiol 2003;56(10):955-62 955 Objectives. To investigate the prognostic factors in patients who come to the emergency room with chest pain but without ST segment elevation. Patients and method. 743 consecutive patients were evaluated by recording clinical history, electrocardiogram and troponin I determination, and early (< 24 h) exercise testing was done for the low-risk subgroup of p...

Recent trends in German life expectancy show a considerable increase. Most of this increase has resulted from decreasing mortality at older ages. Patterns of oldest old mortality (ages 80+) differed significantly between men and women as well as between East and West Germany. While West German oldest old mortality decreased since the mid 1970s, comparable decreases in East Germany did not becom...

Impaired sensory nerve function and axon morphology in mice with diabetic neuropathy 1 2 3 4 Richard C. Lennertz, Karen A Medler, James L. Bain, Douglas E. Wright and Cheryl L. 5 Stucky* 6 7 8 Department of Cell Biology, Neurobiology and Anatomy 9 Medical College of Wisconsin 10 Milwaukee, WI 53226-0509 11 12 Department of Anatomy and Cell Biology 13 University of Kansas Medical Center 14 Kansa...

Effects on intracellular signaling were studied in cells treated with the affibody molecule (ZEGFR:955)2 that targets the epithelial growth factor receptor (EGFR). EGFR is overexpressed in many types of cancers and plays a fundamental role in cell signaling and it is of interest to find targeting agents capable of blocking the receptor. The clinically approved antibody cetuximab (Erbitux) and t...

This paper constructs multirate time discretizations for hyperbolic conservation laws that allow different timesteps to be used in different parts of the spatial domain. The proposed family of discretizations is second order accurate in time and has conservation and linear and nonlinear stability properties under local CFL conditions. Multirate timestepping avoids the necessity to take small gl...