1-Methy-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is a neurotoxin that selectively damages dopaminergic neurons in the substantia nigra pars compacta and induces Parkinson's like symptoms in rodents. Quercetin (QC) is a natural polyphenolic bioflavonoid with potent antioxidant and anti-inflammatory properties but lacks of clinical attraction due to low oral bioavailability. Piperine is a well ...

Next-generation sequencing (NGS) technologies have been widely used in life sciences. However, several kinds of sequencing artifacts, including low-quality reads and contaminating reads, were found to be quite common in raw sequencing data, which compromise downstream analysis. Therefore, quality control (QC) is essential for raw NGS data. However, although a few NGS data quality control tools ...

1 Département de Biologie, Université de Sherbrooke, Sherbrooke, QC, Canada, J1 K 2R1; 2 AG Systematik und Evolutionsbiologie, IBU – Fakultät V, Carl von Ossietzky Universität Oldenburg, 26111 Oldenburg, Germany; 3 Canada Research Chair in behavioural ecology, Département des Sciences Biologiques, Université du Québec à Montréal, P.O. Box 8888, succursale Centre-Ville, Montréal, QC, Canada, H3C...

This paper overviews the basic principles and recent advances in the emerging field of Quantum Computation (QC), highlighting its potential application to Artificial Intelligence (AI). The paper provides a very brief introduction to basic QC issues like quantum registers, quantum gates and quantum algorithms and then it presents references, ideas and research guidelines on how QC can be used to...

Superconducting circuits provide one of the numerous current candidate routes for the realization of quantum computing (QC) technology. In this paper I review the basic physics behind this candidature and outline some superconducting QC proposals currently on the table, demonstrating their common origins. More detailed discussion of the proposals follows, assessing how they measure up to the \D...

Effect of Cyclic Loading on The MR Properties, Compressive Properties, And Biochemical Content of Collagenase-Treated Nucleus Pulposus John Antoniou1, Caroline N. Demers1, Arthur J. Michalek2, Tapas Goswami3, Gilles Beaudoin4, Lorne Beckman3, James C. Iatridis2, Fackson Mwale1 1Lady Davis Institute for Medical Research, McGill University, Montréal, QC, Canada; 2Department of Mechanical Engineer...

Department of Psychiatry, McGill University, Douglas Mental Health University Institute, Montreal, QC, Canada Departments of Psychiatry and Community Health Sciences, Faculty of Medicine, University of Calgary, Calgary, Canada. Centre de Recherche Fernand Seguin, Hôpital Louis-H. Lafontaine, University of Montreal, Montreal, QC Canada Department of Nutrition, Faculty of Medicine, University of ...

This paper shows that pharmaceutical companies and CRO often fail to respond to the recommendations of Good Pharmacovigilance Practices (GVP) by highlighting the lack of efficiency of the quality control (QC) process applied to the pharmacovigilance cases processing. The paper summarized the sampling acceptance statistical theory behind the good statistical practices regarding QC of lots and sh...