The aim of the present study was to evaluate in vitro effects of dietary phytochemicals naringenin, quercetin, and sesamin on the activities of ethoxy- (EROD; CYP1A) and benzyloxy- (BROD; CYP3A) resorufin O-dealkylases after the exposure to the cocktail of persistent organic pollutants (POPs). CD-1 mice were exposed from weaning, through gestation and lactation to a defined mixture of POPs. Hep...

There are well-known limitations and drawbacks on the performance and robustness of the feed-forward, fully-connected Artificial Neural Networks (ANNs), or the so-called Multi-Layer Perceptrons (MLPs). In this study we shall address them by Generalized Operational Perceptrons (GOPs) that consist of neurons with distinct (non-)linear operators to achieve a generalized model of the biological neu...

Institute RECETOX coordinates the “Central and Eastern European Centre for Persistent Organic Pollutants (POPs)” of Stockholm Convention (SC) environmental services: data monitoring, processing, storage and their management. This is supported by the Global Environmental Assessment and Information System (GENASIS) that utilizes data from national and international monitoring networks to obtain a...

We present a new method for the calculation of solvent accessible surface areas at the atomic and residue levels, which we call parameter optimized surfaces (POPS-A and POPS-R ). Atomic and residue areas (the latter simulated with a single sphere centered at the C(alpha)s atom for amino acids and at the P atom for nucleotides) have been optimized versus accurate all-atoms methods. We concentrat...

A partially ordered (generalized) pattern (POP) is a generalized pattern some of whose letters are incomparable, an extension of generalized permutation patterns introduced by Babson and Steingŕımsson. POPs were introduced in the symmetric group by Kitaev [19, 21], and studied in the set of k-ary words by Kitaev and Mansour [22]. Moreover, Kitaev et al. [23] introduced segmented POPs in composi...

BACKGROUND Persistent organic pollutants (POPs)-such as organochlorine pesticides (OCPs), polychlorinated biphenyls (PCBs), and polybrominated diphenyl ethers (PBDEs)-and heavy metals have been reported in sea turtles at various stages of their life cycle. These chemicals can disrupt development and function of wildlife. Furthermore, in areas such as Peninsular Malaysia, where the human consump...

A partially ordered (generalized) pattern (POP) is a generalized pattern some of whose letters are incomparable, an extension of generalized permutation patterns introduced by Babson and Steingŕımsson. POPs were introduced in the symmetric group by Kitaev [19, 21], and studied in the set of k-ary words by Kitaev and Mansour [22]. Moreover, Kitaev et al. [23] introduced segmented POPs in composi...

The pollutants classified as "persistent organic pollutants (POPs)", are being subject to high concern among the scientific community due to their persistence in the environment. TiO2-based photocatalytic process has shown a great potential as a low-cost, environmentally friendly and sustainable treatment technology to remove POPs in sewage to overcome the shortcomings of the conventional techn...

BACKGROUND Environmental exposure to persistent organic pollutants (POPs) may lead to elevation of serum lipids, increasing risk of atherosclerosis with thromboembolism, a recognized cause of stroke. We tested the hypothesis that exposure to contaminants from residence near hazardous waste sites in New York State influences the occurrence of stroke. METHODS The rates of stroke hospital discha...

OBJECTIVE Persistent organic pollutants (POPs), lipophilic chemicals that accumulate mainly in adipose tissue, have recently been linked to type 2 diabetes. However, evidence from prospective studies is sparse. This study was performed to evaluate prospective associations of type 2 diabetes with selected POPs among the elderly. RESEARCH DESIGN AND METHODS Nineteen POPs (14 polychlorinated bip...