Contribution change of factor costs analysis may help managers in decision making and in adjusting to changes. Over the last two decades, production and enhancement of kutum fingerlings have increased in Iran, reaching to more than 229 million fingerlings by 2005, but declined to 187 million from 2005 to 2008. Over the years 2002-2006, a study of fingerling production costs for kutum fish was ...

enter hospitals each day following suicide attempts or self-inflicted injuries, a number that could be greatly reduced through improved community-based intervention strategies and greater awareness of groups most at risk for self-harm, according to the Canadian Institute for Heath Information (CIHI). About 17 482 Canadians were admitted to hospitals for overnight stays as a result of self-infli...

OBJECTIVE Data from electronic healthcare records (EHR) can be used to monitor drug safety, but in order to compare and pool data from different EHR databases, the extraction of potential adverse events must be harmonized. In this paper, we describe the procedure used for harmonizing the extraction from eight European EHR databases of five events of interest deemed to be important in pharmacovi...

We perturbed the growth rate estimates for the resistant mutants by the multiplicative random factor (1 + 0.2 · U [−1, 1]) representing a 20% noise level, and performed 100 randomized trials. Table S1 shows the probability of sensitivity to imatinib (I), dasatinib (D), imatinib + dasatinib (I+D), and imatinib + dasatinib + nilotinib (I+D+N) for the baseline unperturbed growth rates, as well as ...

OBJECTIVE To investigate the trends in the incidence of gonorrhoea through an extended period of time and to compare the epidemiology of gonorrhoea infection between 2 distinct ethnic groups (Jews and Arabs). DESIGN A retrospective population-based cohort study was conducted on all consecutive patients diagnosed with gonorrhoea through the years 2001-2015. SETTING National Department of Epi...

BACKGROUND Current cancer mortality statistics are important for public health decision-making and resource allocation. Age-standardized rates and numbers of deaths are predicted for 2016 in the European Union (EU). PATIENTS AND METHODS Population and death certification data for stomach, colorectum, pancreas, lung, breast, uterus, prostate, leukaemias and total cancers were obtained from the...

OBJECTIVE This cohort study evaluates the unknown age-specific and gender-specific incidence of primary shoulder dislocations in the UK. SETTING UK primary care data from the Clinical Practice Research Datalink (CPRD) were used to identify patients aged 16-70 years with a shoulder dislocation during 1995-2015. Coding of primary shoulder dislocations was validated using the CPRD general practi...

INTRODUCTION Early-onset dementia (EOD) is defined as dementia with onset before the age of 65 years. EOD is increasingly recognised as an important clinical and social problem with devastating consequences for patients and caregivers. OBJECTIVE Determine the annual crude incidence rate and the specific incidence rates by sex and age in patients with EOD, and the standardised rate using the l...

BACKGROUND There are few published data describing the mortality burden associated with influenza and respiratory syncytial virus (RSV) infection in children in low- and middle-income countries and particularly from Africa and settings with high prevalence of human immunodeficiency virus (HIV). METHODS We modeled the excess mortality attributable to influenza (seasonal and pandemic) and RSV i...

OBJECTIVES To estimate the incidence and prevalence of systemic lupus erythematosus (SLE) in the UK over the period 1999-2012. METHODS A retrospective cohort study using the Clinical Practice Research Datalink (CPRD). The incidence was calculated per 100 000 person-years and the prevalence was calculated per 100 000 people for the period 1999-2012 and stratified by year, age group, gender, re...