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We describe a new approach for cluster-based drawing of large graphs, which obtains clusters by using binary space partition (BSP) trees. We also introduce a novel BSP-type decomposition, called the balanced aspect ratio (BAR) tree, which guarantees that the cells produced are convex and have bounded aspect ratios. In addition, the tree depth is O(log n), and its construction takes O(n log n) t...
An (n; s) Davenport{Schinzel sequence, for positive integers n and s, is a sequence composed of n distinct symbols with the properties that no two adjacent elements are equal, and that it does not contain, as a (possibly non-contiguous) subsequence, any alternation a b a b of length s + 2 between two distinct symbols a and b. The close relationship between Davenport{Schinzel sequences and the c...
BACKGROUND The concentrations of circulating adipokines in dogs with myxomatous mitral valve disease (MMVD) have not been investigated in detail. OBJECTIVES To determine whether serum concentrations of adipokines differ between healthy dogs and dogs with MMVD and whether circulating concentrations depend on the severity of heart failure resulting from MMVD. ANIMALS In the preliminary study,...
OBJECTIVE The purpose of this study was to characterize the urinary microbiota in women who are planning treatment for urgency urinary incontinence and to describe clinical associations with urinary symptoms, urinary tract infection, and treatment outcomes. STUDY DESIGN Catheterized urine samples were collected from multisite randomized trial participants who had no clinical evidence of urina...
PURPOSE To study the association of ARMS2 A69S genotype with the development of exudative age-related macular degeneration (AMD) in the unaffected fellow eye and to estimate the duration until the development of AMD in the second eye. DESIGN Retrospective cohort study. METHODS We retrospectively reviewed 326 patients who had exudative AMD in at least 1 eye, genotyping of ARMS2 A69S, and a m...
Background: Chronic hemodialysis (HD) in the 1960s encompassed a wide variety of prescriptions from twice weekly to five times per week HD. Over time, HD prescriptions in the West became standardized at three times per week, 2.5–4 h per session, with occasional additional treatments for volume overload. Summary: When clinical trials of dialysis dose failed to show significant benefit of extendi...
We present kinetic data structures for detecting collisions between a set of polygons that are not only moving continuously but whose shapes can also vary continuously with time. Unlike classical collision detection methods that rely on bounding volume hierarchies, our method is based on deformable tilings of the free space surrounding the polygons. The basic shape of our tiles is that of a pse...
The prevalence and significance of genetic abnormalities in older patients with acute myeloid leukemia (AML) are unknown. Polymerase chain reactions and single-stranded conformational polymorphism analyses were used to examine 140 elderly AML patients enrolled in the Southwest Oncology Group study 9031 for FLT3, RAS, and TP53 mutations, which were found in 34%, 19%, and 9% of patients, respecti...
In this paper we give a comprehensive overview of features devised for Web spam detection and investigate how much various classes, some requiring very high computational effort, add to the classification accuracy. • We collect and handle a large number of features based on recent advances in Web spam filtering, including temporal ones, in particular we analyze the strength and sensitivity of l...
PURPOSE The lack of effective treatment for localized esosphageal cancer leads to poor patient outcome. Nuclear factor kappaB (NF-kappaB), a transcriptional factor, is constitutively activated or treatment induced in esophageal cancer and may influence treatment outcomes. PATIENTS AND METHODS Pre- and post-treatment cancer specimens from patients enrolled onto a clinical trial were studied fo...
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