Results In our cohort (148 males and 120 females) fever began at 26.2 + 24 months of age. 8% of the patients had an onset after the fifth year of life, but all other Thomas criteria were met. A family history was present in 39.6% of patients. Mean duration of PFAPA episodes was 4 + 1.6 days, and a mean interval between episodes 27.9 + 11 days. Most common symptoms with fever were pharyngitis (9...

UNLABELLED BACKGROUND In addition to stimulating linear growth in children, growth hormone (GH) influences metabolism and body composition. These effects should be considered when individualizing GH treatment as dose-dependent changes in metabolic markers have been reported. HYPOTHESIS There are different dose-dependent thresholds for metabolic effects in response to GH treatment. METHOD...

The highly restricted distribution of human folate receptor-alpha (FRα) in normal tissues and its high expression in some tumors, along with its putative role in tumor cell transformation, make this antigen a suitable target for antigen-specific, monoclonal antibodybased immunotherapy for oncology indications. We have developed a therapeutic humanized monoclonal antibody with high affinity for ...

BACKGROUND Exacerbated postparturient insulin resistance (IR) has been associated with several pathologic conditions in dairy cattle. Oxidative stress (OS) plays a causative role in IR in humans, and an association, but not direct relationship, between OS and IR recently has been reported in transition dairy cattle. HYPOTHESIS Supplementation with antioxidants shortly before calving improves ...

Let G be a finite group and k be a field of characteristic p. We investigate the homotopy category K(Inj kG) of the category C(Inj kG) of complexes of injective (= projective) kG-modules. If G is a p-group, this category is equivalent to the derived category Ddg(C(BG; k)) of the cochains on the classifying space; if G is not a p-group it has better properties than this derived category. The ord...

Resneha de PLATÃO. Teeteto. Texto estabelecido e anotado por John Burnet. Tradução, apresentação notas Maura Iglésias Fernando Rodrigues. Rio Janeiro; São Paulo: Editora PUC-Rio; Edições Loyola, 2020. 264 pp. ISBN (PUC-Rio): 978-65-991801-0-1. (Edições Loyola): 978-65-5504-040-1.