BACKGROUND Nonmodulation seems to represent an inheritable trait characterized by abnormal angiotensin-mediated control of aldosterone release and renal blood supply and salt-sensitive hypertension. Recently, we demonstrated that atrial natriuretic peptide (ANP) response to angiotensin II also is altered in nonmodulators. Moreover, an abnormal ANP response to acute volume expansion has been sho...

BACKGROUND AND AIMS The small leafy succulent shrub Halocnemum strobilaceum occurs in saline habitats from northern Africa and Mediterranean Europe to western Asia, and it is a dominant species in salt deserts such as those of north-west China. The effects of temperature, light/darkness and NaCl salinity were tested on seed germination, and the effects of salinity were tested on seed germinatio...

We compared the effects of sodium meclofenamate (5 mg/kg i.v.), an inhibitor of prostaglandin synthesis, on renal function in six unanesthetized dogs maintained for 5 to 7 days before the experiment on 100 mEq/day of NaCl and after sodium depletion by furosemide administration and salt deprivation. Plasma renin activity (PRA) during sodium depletion (12.35 +/- 3.93 ng ml-1 hr-1) was higher than...

In this experiment soybean seeds were pre-treated with salt tolerant isolate of Trichoderma harzianum to evaluate the different aspects of seedling growth and metabolism in response to different concentrations of NaCl. Trichoderma isolate was more effective in improving dry weight and root volume of seedlings during mild salt stress. Seedlings obtained from bioprimed seeds had significantly hig...

In the management of metastatic breast cancer, fewer recognized therapeutic standards are available as compared to the early stages of the disease. Thus, it is pertinent to search for new, effective therapy to improve survival, tolerability and quality of life of patients. In this study, a liposomal formulation was developed for a novel dihydrofolate reductase (DHFR) inhibitor, M-V-05. Drug enc...

Neural activity in intact chorda tympani nerve of rats was studied with an electronic summator. Neural activity increased when amino acid solutions 0.01 M or above passed over the tongue. Response magnitude, at concentrations close to solubility limits for the amino acids tested, was: DL-methionine < DL-tryptophan < DL-valine < DL-alanine < glycine < 0.1 M NaCl. Maximum response magnitudes to 1...

Antibodies to chromatin proteins of Novikoff hepatoma cells formed precipitin bands in the double-diffusion immunoprecipitation assay with chromatin proteins of Novikoff hepatoma, Walker 256 carcinosarcoma, and 18-day fetal rat liver. The antigen used for preparation of antiserum was the chromatin proteins initially extracted with 3 M NaCl-7 M urea and soluble after dialysis to 0.14 M NaCl-0.35...