Background Depression is a common manifestation of Alzheimer’s disease (AD) and frequently observed at the early phase disease. Several postmortem studies demonstrated that tau deposition was found brainstem nuclei including locus coeruleus (LC) dossal raphe nucleus (DRN) (3, 4), even before Braak stages neurofibrillary tangle pathology. Given disturbance monoaminergic system related to depress...

Background: The growing body of evidence demonstrates both the desirable and undesirable consequences organizational silence. This study aims to explore influence climate silence on job performance through mediating effects work engagement (WE). Further, degree which supervisor support (SS) moderate are examined. Methods: A quantitative cross-sectional design was used for study. Survey data fro...