Earlier methods adopted for the estimation of median lethal dose (LD50) used many animals (40 – 100). But for the up – and – down procedure, 5 – 15 animals can be used, the number I still consider high. So this paper seeks to adopt arithmetic, geometric and harmonic (AGH) mean for rough estimation of median lethal dose (LD50) using up – and – down procedure by using 2 – 6 animals that may likel...

Topic detection and tracking (TDT) algorithms have long been developed for the discovery of topics. However, most existing TDT algorithms suffer from paying less attention to: (1) temporal distance between a pair of topics; (2) the mutual effect between highly correlated topic terms. In this paper, we proposed a novel topic detection approach by applying hierarchical clustering on the construct...

Hirschsprung disease (HSCR) exhibits complex genetics with incomplete penetrance and variable severity thought to result as a consequence of multiple gene interactions that modulate the ability of enteric neural crest cells to populate the developing gut. As reported previously, when the same null mutation of the Ednrb gene, Ednrb(sl), was introgressed into the F344 strain, almost 60% of F344-E...

We present a database of 21 bond dissociation energies for breaking metal-ligand bonds. The molecules in the metal-ligand bond energy database are AgH, CoH, CoO+, CoOH+, CrCH3+, CuOH2+, FeH, Fe(CO)5, FeO, FeS, LiCl, LiO, MgO, MnCH3NiCH2+, Ni(CO)4, RhC, VCO+, VO, and VS. We have also created databases of metal-ligand bond lengths and atomic ionization potentials. The molecules used for bond leng...

G. Borges for the NA50 Collaboration B. Alessandro, C. Alexa, R. Arnaldi, M. Atayan, S. Beolè, V. Boldea, P. Bordalo, G. Borges, C. Castanier, J. Castor, B. Chaurand, B. Cheynis, E. Chiavassa, C. Cicalò, M.P. Comets, S. Constantinescu, P. Cortese, A. De Falco, N. De Marco, G. Dellacasa, A. Devaux, S. Dita, J. Fargeix, P. Force, M. Gallio, C. Gerschel, P. Giubellino, M.B. Golubeva, A.A. Grigorya...