A new neolignan glycoside, (7R,8R)-7,8-dihydro-9'-hydroxyl-3'-methoxyl- 8-hydroxymethyl-7-(4-hydroxy-3-methoxyphenyl)-1'-benzofuranpropanol 9'-O-beta-D- glucopyranoside (1) was isolated from the leaves of Acer truncatum along with (7R,8R)-7,8-dihydro-9'-hydroxyl-3'-methoxyl-8-hydroxymethyl-7-(4-O-alpha-L-rhamno- pyranosyloxy-3-methoxyphenyl)-1'-benzofuranpropanol (2), schizandriside (3), lyonir...

Leguminosae, Erythrina, Pterocarpans, Isoflavans, Phytoalexins Two new phytoalexins isolated from the fungus-inoculated leaflets of Erythrina sandwicensis have been identified as (—)-6aS; 11 aS-3,6 a,9-trihydroxy-10-isopentenylpterocarpan (sandwicarpin) and (—)-6a/?; 11 a^-3-hydroxy-9-methoxy-10-isopentenylpterocaipan (sandwicensin). These compounds co-occur with several known pterocarpan (deme...

Three new iridoids, Gardenal-I (1), Gardenal-II (2) and Gardenal-III (3), together with nine known iridoid glycosides; geniposide (4), 6-β-hydroxy geniposide (5), 6-α-hydroxy geniposide (6), 6-α-methoxy geniposide (7), feretoside (8), genipin-1-β-gentiobioside (9), shanzhiside (10), lamalbidic acid (11) and picrocrocinic acid (12) were isolated from EtOH extract of G. gasminoides. The structure...

N-Hydroxy-2-acetylaminofluorene (N-hydroxy-AAF), in conjugated form, was identified as a urinary metabolite of 2-acetylaminofluorene (AM') in male mongrel dogs. This metabolite was isolated and characterized in crystalline form. 7-Hydnoxy AM', in conjugated form, and AM? were also found in the urine of dogs fed AAF; no 1-, 3-, or 5-hydroxy-AAF was detected. The ingestion of N-hydroxy-AAF led to...

We isolated seven terpenes and five phenolic constituents from the aerial parts of Lactuca indica L. using column chromatographic separation of its MeOH extract. Their structures were determined by spectroscopic methods to be trans-phytol (1), 3beta-hydroxyglutin-5-ene (2), 5,6-epoxy-3-hydroxy-7-megastigmen-9-one (3), 11beta-13-dihydrolactucin (4), 2-phenylethyl beta-D-glucopyranoside (5), cich...

Reaction of substituted-aniline (8) with ethyl (l-methyl-5-nitroimidazole-2- carbonyl) acetate (9) gave 4-hydroxy-2-(l-methyl-5-nitro-2-imidazolyl)- substituted-quinolines (lo), which were converted to compound 11 with phosphorus oxychloride. Substituted-2-(l-methyl-5-nitro-2-imidazo1yl)-4.- methyl-(or phenyl-) quinolines (14) were prepared through the reaction of 2- acetyl-5-nitro-1-methy...