In this paper we consider the contextual multi-armed bandit problem for linear payoffs under a risk-averse criterion. At each round, contexts are revealed arm, and decision maker chooses one arm to pull receives corresponding reward. particular, mean-variance as risk criterion, best is with largest We apply Thompson sampling algorithm disjoint model, provide comprehensive regret analysis varian...

OBJECTIVE Maximal oxygen uptake (Vo(2max)) of 44 ml kg(-1) min(-1) is an accepted criterion (Vo(2CR)) below which health and fitness for young male adults may be compromised. New algorithms validated for Vo(2CR) screening using the 20 m multistage shuttle run test (20mMST) were developed. METHODS Vo(2max) was assessed in 110 males using a stationary gas analyser in a treadmill test (TT) and i...

OBJECTIVES Our objective was to assess the effect of Therapeutic Touch (TT) on the proliferation of normal human cells in culture compared to sham and no treatment. Several proliferation techniques were used to confirm the results, and the effect of multiple 10-minute TT treatments was studied. DESIGN Fibroblasts, tendon cells (tenocytes), and bone cells (osteoblasts) were treated with TT, sh...

A summer study and a winter study were conducted using an incomplete factorial structure in a complete randomized design. Within season, the factors studied were 1) type of diet, which included 2 levels of ME, classified as either concentrate (3.04 Mcal of ME/kg) or roughage (2.63 Mcal of ME/kg) diets, and 2) daily ME intakes (MEI) of 11, 18, and 25 Mcal of ME/d for the roughage diets and 18, 2...

Background: Epigenetic factors such as non-coding RNA (miRNA) have been shown to be deregulated in Systemic Lupus Erythematosus (SLE). In mouse models, different miRNAs associated with lupus nephritis (LN), one of the most severe manifestations disease 1 . Objectives: To evaluate expression miR-155 and miR-34a renal tissues biomarkers organ involvement inflammatory tissue activity patients LN. ...

We consider the assignment problem between two sets of $N$ random points on a smooth, two-dimensional manifold $\Omega$ unit area. It is known that average cost scales as $E_{\Omega}(N)\sim\frac{1}{2\pi}\ln N$ with correction at most order $\sqrt{\ln N\ln\ln N}$. In this paper, we show that, within linearization approximation field-theoretical formulation problem, first $\Omega$-dependent const...

INTRODUCTION The VX2 carcinoma is well established as a useful model for studies on treatment of primary tumors of various locations including the rabbit's auricle; however, limited experience exists on the treatment modalities of lymph node (LN) metastases. In this investigation we studied the frequency and extent of lymphogenic metastatic spread of auricular VX2-carcinomas and their response ...

The benzene metabolite trans,trans-muconic acid (tt-MA) is widely used as a biological indicator of exposure to this xenobiotic. An analytical method was developed and validated for the determination of urinary tt-MA using solid phase extraction onto a Strata SAX cartridge. The analysis was performed by HPLC with an Aminex HPX-87H ion exclusion column and a UV diode array detector. The sample p...

Leg thermotherapy (TT) application reduces blood pressure (BP) and increases both limb blood flow and circulating levels of anti-inflammatory mediators in healthy, young humans and animals. The purpose of the present study was to determine the impact of TT application using a water-circulating garment on leg and systemic hemodynamics and on the concentrations of circulating cytokines and vasoac...

Accurate cosmological parameter estimates using polarization data of the cosmic microwave background (CMB) put stringent requirements on map calibration, as highlighted in recent results from Planck satellite. In this paper, we point out that a model-dependent determination calibration can be achieved by joint fit temperature-E-mode cross-power spectrum (TE) and E-mode auto-power (EE). This pro...