Pulmonary hypertension and cor pulmonale have been shown to worsen prognosis increase the risk of death in adult patients with cystic fibrosis (CF). To evaluate arterial stiffness (AS) functional state left right parts heart CF patients. 50 (25 M/ 25 F, mean age 26 ± 6 yrs) 52 volunteers (20 32 27 were examined. Echocardiography was performed only AS measurements using VaSera VS-1500N: cardio-a...

by Richard T. Lindsey, Ph.D. ad the incidence rates of adult obesity resting between 15 percent and 50 percent (Bray, 1976) and with 25 percent of American youth being obese, an important challenge presents itself for practitioners of health care. In sheer numbers these statistics represent approximately 34 million people (Van Itallie, 1985). Not only do the obese bear the brunt of social ridic...

BACKGROUND High-producer TGFβ1 genotypes are associated with severe lung disease in cystic fibrosis (CF), but studies combining IL-8, TNFα-, and TGFβ1(+genotype) levels and their impact on CF lung disease are scarce. AIM Assessing the relationship between TGF β 1, IL-8, and TNF- α and lung disease in CF in an exacerbation-free interval. METHODS Twenty four patients delta F508 homozygous (me...

BACKGROUND over the last 25 years several national registries of CF have been set up. Such systems can be very useful in providing an integrated resource for improving patient care and conducting research on the disease. Minimum Data Set is a common set of data items that should be used to collect and report data in the registry. The principal aim of this research was to determine minimum data ...

BACKGROUND Research that explores stigma in Cystic Fibrosis (CF) is limited. Productive cough, repeated lung infections, and periods of serious illness requiring hospitalizations are among common symptoms of CF. These symptoms may cause a negative perception by others. We developed a CF-specific Stigma Scale and tested its psychometric properties. METHODS We conducted a focus group with 11 pa...

To learn whether surface force changes precede the appearance of lung edema during experimental intoxication due to paraquat, we studied rats for 1 day following injection of 27 mg/kg iv. By 24 h, surface-active material recovered by lung lavage was decreased 32 percent, and changes in lung microsections and recoil pressure at half-deflation suggested decreased alveolar stability. Despite a 25 ...

Stark, G. D., and Drummond, M. (1973). Archives of Disease in Childhood, 48, 676. Results of selective early operation in myelomeningocele. In a 6-year period 163 unselected newborn infants with open myelomeningocele were assessed. 48%, considered to have the most favourable prognosis, were selected for early back closure and vigorous subsequent treatment. The more severely affected remainder w...

Several investigators have demonstrated a sequential synthesis of 19 S and 7 S antibodies upon antigenic stimulation; commonly there is a transient early 19 S response followed subsequently by 7 S production (1-6). The nature of the antigen, however, can influence the kinetics of the 19 S and 7 S antibody response. Thus, certain polysaccharide antigens are known to induce a long lasting 19 S an...

Sodium ion and chloride transport was studied in vitro in small intestinal and colonic tissue from patients with cystic fibrosis (CF) and from non-CF control subjects matched as to age and sex. Normal histological appearance and substantial response to mucosal glucose (5 mM, ileum) or mucosal amiloride (10(-5) M, colon) indicated normal tissue viability in both control and CF tissues. Electrone...

this study was conducted to study the effect of organic acids on the preservation of alfalfa nutritional value after harvesting. a split plot design with 4 treatments and 3 times was conducted in which organic acids were sprayed on the 30percent moisture content forage before baling. treatments were: 1) forage without additives as control, 2) pure propionic acid, 1percent, 3) acetic acid percen...