When desialylated ceruloplasmin (ASCPN), labeled with 64Cu and with 3H in its galactose residues, is injected intravenously into a rat, more than half of the radioactivity can be recovered within minutes in ASCPN precipitated immunochemically from liver homogenates. Both radioautographic studies and measurements of hepatic uptake of ASCPN following blockade of the reticuloendothelial system ind...

Grahame-Smith, D. G. & Parfitt, A. (1970) J. Neurochem. 17, 1339-1353 Green, A. R. & Youdim, M. B. H. (1975) Br. J. Pharmacol. 55,415-422 Hawkins, R. A., Williamson, D. H. & Krebs, H. A. (1971) Biochem. J . 122.13-18 Hawkins, R. A., Miller, A. L., Nielsen, R. C. & Veech, R. L. (1973) Biochem. J. 134,1001-1008 Horst, W. D. &Jester, J. (1971) Life Sci. 10, 685-689 Horst, W. D., Bautz, G., Renyi, ...

The cause of corticosteroid-induced hyperlipoproteinemia was studied in rats and mice. An ultrastructural morphometric method was utilized to demonstrate alterations in hepatocyte very low density lipoprotein content, and Triton WR 1339-treated rats were used to identify changes in the removal of very low density lipoproteins from plasma. The results show that corticosteroid treatment results i...

Calibration of ρ Values for Testing Precise Null Hypotheses Thomas Sellke, M. J Bayarri & James O Berger a Thomas Sellke is Professor, Statistics Department, Purdue University, West Lafayette, IN 47907-1339. M. J. Bayarri is Professor, Department of Statistics and Operations Research, University of Valencia, Burjassot, Valencia 46100, Spain. James O. Berger is Arts and Sciences Professor, Insti...

BACKGROUND The effectiveness of creatine in treating Parkinson's disease (PD) has not been conclusively determined. Therefore, we performed a meta-analysis to address this issue. METHODS The Cochrane Central Register of Controlled Trials, PUBMED, EMBASE, and other databases were searched, and outcomes measured by the Total Unified Parkinson's Disease Rating Scale (UPDRS) and the Schwab & Engl...

Ruthenium(III) complexes are promising candidates for anticancer drugs, especially the clinically studied indazolium trans-[tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019) and its analogue sodium trans-[tetrachlorobis(1H-indazole)ruthenate(III)] (NKP-1339). Several studies have emphasized the likely role of human serum proteins in the transportation and accumulation of ruthenium(III) comple...

Cryo-TEM was carried out on samples containing polyelectrolyte-micelle complexes, formed by combining poly(diallyldimethylammonium chloride) (PDADMAC), a strong cationic polyelectrolye, with oppositely charged mixed micelles of sodium dodecyl sulfate (SDS) and nonionic Triton X-100 (TX100), in 0.40 M NaCl. Complexation appears to involve the formation of micelle-rich regions, presumably within ...

OBJECTIVE To determine the prevalence of vitamin A deficiency in children aged 6-9 years in northern Ethiopia. METHODS A cross-sectional study was carried out and the data were analysed for 824 (61.5%) of 1339 eligible children for whom there was complete information on biochemical vitamin A status, dietary vitamin A intake, ocular examination for xerophthalmia, and anthropometry. FINDINGS ...

BACKGROUND Surgical site infections are one of the most common post-operative complications encountered by foot and ankle surgeons. The incidence reported in the literature varies between 0.5 and 6.5%. The results of a 12-month Australia-wide clinical audit analysing the rates of postoperative infections in association with podiatric surgery are presented. METHODS De-identified patient data w...

The relative importance of genetic and environmental factors for stress coping styles, age and gender differences, and the relationship between coping styles and personality traits were assessed in middle-aged and older adult twins reared apart and reared together, as part of the ongoing Swedish Adoption/Twin Study of Aging (SATSA). The Billings and Moos Coping Measure was administered to 1339 ...