Background: The injection of retrobulbar block is associated with significant pain and discomfort. Therefore a short-acting IV analgesic before retrobulbar injection has been advocated. Objective: To compare remifentanil, alfentanil and fentanyl in providing analgesia for retrobulbar block injection. Methods: 69 patients were enrolled randomly into three groups of 23 each to receive either Remi...

OBJECTIVE: The application of a laser scanning technique to measure regional cerebral blood flow (CBF) and tissue hemoglobin oxygenation (HbO2) using the rat closed cranial window preparation is described. METHODS: Twenty-nine male Wistar rats were used to consecutively measure local CBF by laser Doppler flowmetry and tissue HbO2 by a microspectrophotometric method at multiple corresponding cor...

A global protein survey is needed to gain systems-level insights into mammalian cell signaling and information flow. Human Jurkat T leukemic cells are one of the most important model systems for T cell signaling study, but no comprehensive proteomics survey has been carried out in this cell type. In the present study we combined subcellular fractionation, multiple protein enrichment methods, an...

Previous research has established that cognitive theory-based depression prevention programs aiming change in negative cognitive style in early adolescents do not have strong effects in universal settings. Although theories suggest that a negative cognitive style precedes depressive symptoms, empirical findings are mixed. We hypothesized that negative cognitive style may not predict depressive ...

Autism is a complex genetic disorder where both de-novo and inherited genetics factors play a role. Next generation sequencing approaches have been extensively used to identify rare variants associated with autism. To date, all such studies were focused on nuclear genome; thereby leaving the role of mitochondrial DNA (mtDNA) variation in autism unexplored. Recently, analytical tools have been d...

abiraterone 671 absolute risk increase 913 absolute risk reduction 913 accelerated/dose-dense chemotherapy 305 active surveillance 888 acute lymphoblastic leukaemia 1026 acute myeloid leukaemia 1026 acyl-CoA synthetase 1369 acylpeptide hydrolase (ACPH, EC 3.4.19.1) 723 ADCC 113 adenocarcinoma 1400 adenoma 1674 adiposity 578 adjuvant chemotherapy 732 adjuvant radiotherapy 913 adjuvant therapy 15...

BACKGROUND In this study, we assessed the prognostic value of the lymph node ratio (LNR), established a hypothetical tumor-ratio-metastasis (TRM) staging system and compared it with the 7th edition International Union Against Cancer pathological N (pN) and tumor-node-metastasis (TNM) system. PATIENTS AND METHODS A total of 1343 gastric cancer patients undergoing D2 resection were staged using...

miRNAs are endogenous small RNA (sRNA) that play critical roles in plant development processes. Canna is an ornamental plant belonging to family Cannaceae. Here, we report for the first time the identification and differential expression of miRNAs in two contrasting flower color cultivars of Canna, Tropical sunrise and Red president. A total of 313 known miRNAs belonging to 78 miRNA families we...

Posttraumatic stress disorder (PTSD), a pathologic response to severe stress, is a common co-morbid disorder in substance-dependent individuals. Evidence from twin studies suggests that PTSD is moderately heritable. Genetic association studies to date have reported a limited number of replicated findings. We conducted a candidate gene association study in trauma-exposed individuals within the C...

(n, k) [370]. (N − 1) [1203]. + [1117, 903]. 0 [349, 852]. 1 [32, 939, 293, 778, 516, 916, 607, 563, 548, 946, 231, 852, 578]. 1, 1 [488]. 2 [1234, 1246, 737, 714, 715, 313, 788, 92, 166, 202]. 2.5n [535]. 3 [1234, 313, 92, 202]. 7 [1141]. ∗ [466]. α− β [235]. α2 [1355]. B [515]. B∗ [442]. B [680]. mod5 [1141]. P [1090]. QH [1090]. D [1209, 401, 136, 1078, 1017, 1185]. DTIMEF(F) =?DSPACEF(F) [1...