Background Myocardial BOLD MRI is an emerging non-contrast approach for the assessment of ischemic heart disease. However, current BOLD CMR methods (T2-weighted, T2*-weighted or bSSFP) are limited by poor spatial coverage and image artifacts (e.g. coil bias, B1 and B0 inhomogeneities). To address these limitations, we developed a fast, free breathing 3D T2 mapping technique at 3T that utilizes ...

The uptake of HNO3 to deliquescent airborne seasalt particles (RH = 55%, P = 760 torr, T = 300 K) at concentrations from 2 to 575 ppbv is measured in an aerosol flow tube using 13N as a tracer. Small particles (≈ 70 nm diameter) are used in order to minimize the effect of diffusion in the gas phase on the mass transfer. Below 100 ppbv, an uptake coefficient (γupt) of 0.50 ± 0.20 is derived. At ...

A 71-year-old male with known bronchiectasis and atrial fibrillation was admitted to Seoul St. Mary's Hospital with recurrent transient ischemic attack. Radiofrequency ablation was performed to resolve the patient's atrial fibrillation, but failed. However, a fistula between the left circumflex artery and the bilateral bronchial arteries was found on computed tomography. Fistula ligation and a ...

OBJECTIVE Accurate identification of primary central nervous system lymphoma (PCNSL) and its differentiation from other brain tumors remain difficult but are essential for treatment. In this study, we investigated whether (13)N-ammonia combined with (18)F-FDG could distinguish PCNSL from solid gliomas effectively. METHODS Ten consecutive patients with final diagnosis of PCNSL (5 female and 5 ...

Alpha-fetoprotein (AFP)-negative hepatocellular carcinoma (ANHCC) patients account for more than 30% of the whole entity HCC and are easily misdiagnosed. This three-phase study was designed to find validate new ANHCC N-glycan markers which identified from The Cancer Genome Atlas (TCGA) database noninvasive detection. Differentially expressed genes (DEGs) biosynthesis degradation related were sc...

Introduction Range and diffusion of positron-emitting radiopharmaceuticals are important parameters for image resolution in positron emission tomography (PET). In this study, GEANT4 toolkit was applied to study positron diffusion in soft tissues with and without a magnetic field for six commonly used isotopes in PET imaging including 11C, 13N, 15O, 18F, 68Ga, and 82Rb. Materials and Methods GEA...

OBJECTIVE Silent myocardial ischemia is common in asymptomatic subjects without a prior history of coronary artery disease (CAD) and is associated with increased morbidity and mortality. Our objective was to determine whether endothelial dysfunction is associated with silent myocardial ischemia and whether the association is independent of genetic and familial factors. MATERIAL AND METHODS We...