A 52-year-old man was brought to the emergency department because of multiple implantable cardioverterdefibrillator (ICD) shocks. His existing dual-chamber pacemaker was upgraded from a biventricular ICD 4 years ago. The ECG in the emergency department showed sinus tachycardia with left bundle-branch block at a rate of 135 bpm. In the emergency department, the patient received 5 additional shoc...

course. All ages are affected and the diagnosis must be considered if there is a modest degree of sinus bradyeardia (SB), even if asymptomatic, as SB is less benign than was heretofore thought. Inappropriate or relatively slow sinus rates (RSSR) under stressful conditions are equally as important as SB. Inadequacy of the sinoatrial node (SAN) may be manifested by one or more of the following: (...

Atrioventricular nodal reentrant tachycardia (AVNRT) is a relatively common paroxysmal supraventricular tachycardia. This study investigated whether adenosine-5'-triphosphate (ATP) injection during sinus rhythm might be useful in the noninvasive diagnosis of dual AV nodal pathways. The study group consisted of 9 patients with slow/fast AVNRT and 11 control patients without antegrade dual AV nod...

course. All ages are affected and the diagnosis must be considered if there is a modest degree of sinus bradyeardia (SB), even if asymptomatic, as SB is less benign than was heretofore thought. Inappropriate or relatively slow sinus rates (RSSR) under stressful conditions are equally as important as SB. Inadequacy of the sinoatrial node (SAN) may be manifested by one or more of the following: (...

HOLMES, J. E. AND Mr. R. ADEY. Electrical activity of the entorhinal cortex during conditioned behavior. Am. J. Physiol. I 99 (5) : 741-744. 1960.-A 4-6-cps wave form was observed in the entorhinal cortex of 8 out of IO cats studied with the implanted electrode technique. When the animals were trained to approach a concealed food reward, the slow waves always accompanied the act of walking to t...

Background—Biological pacing performed solely via HCN2 gene transfer in vivo results in relatively slow idioventricular rates and only moderate autonomic responsiveness. We induced biological pacing using the Ca -stimulated adenylyl cyclase AC1 gene expressed alone or in combination with HCN2 and compared outcomes with those with single-gene HCN2 transfer. Methods and Results—We implanted adeno...

The binding of specific ligands to neutrophil cell surface receptors and the association of these receptors with the cytoskeleton may represent an essential step in activation. To identify surface proteins that are linked to the cytoskeleton during activation, neutrophil 125I-surface labeled plasma membranes were extracted with Triton X-100, and the soluble and insoluble (cytoskeleton) fraction...

Case report A 78-year-old woman with hypertension, paroxysmal atrial fibrillation treated with pulmonary vein isolation 4 years prior, and normal biventricular systolic function presented with symptomatic high-grade heart block with junctional escape rhythm and QRS duration of 84 ms (Figure 1A). She underwent dual-chamber pacemaker implantation with apical RV lead placement and resolution of he...

Scenario: This lead II ECG rhythm strip was obtained in a 52-year-old male patient being treated in the neurological intensive care unit for subarachnoid hemorrhage. The patient was unconscious and therefore could not be asked whether he was experiencing symptoms. His vital signs were stable: His blood pressure was 125/70, heart rate was 80 beats per minute (bpm), and he was receiving mechanica...