BACKGROUND We aimed to investigate the relationship between potentially modifiable risk factors in middle age and disability after 13 years using the Framingham Offspring Study (FOS). We further aimed to develop a disability risk algorithm to estimate the risk of future disability for those aged 45-65 years. METHODS FOS is a longitudinal study. We used examination 5 (1991-1995; 'baseline') an...

ion,level of, 24access-fixed code, 150, 217access-restricted code, 149, 217algorithm,biconnectivity, 114binary search, 94closest pair, 98halving merge, 54k-D tree, 96line-drawing, 50line-of-sight, 40, 105linear-systems, 118matrix-vector multiply, 117maximal-independent-set, 114maximum-flow, 114merge-hull, 103minimum-spanning-tr...

BACKGROUND Echocardiography has been a popular modality used to aid in the diagnosis of infective endocarditis (IE) with the modified Duke criteria. We evaluated the necessity between the uses of either a transthoracic echocardiography (TTE) or transesophageal echocardiography (TEE) in patients with a body mass index (BMI) greater than or equal to 25 kg/m(2) and less than 25 kg/m(2). METHODS ...

BACKGROUND Postoperative complications are associated with reduced fitness. Cardiopulmonary exercise testing (CPET) has been used in risk stratification. We investigated the relationship between preoperative CPET and in-hospital morbidity in major colonic surgery. METHODS We prospectively studied 198 patients undergoing major colonic surgery (excluding neoadjuvant cancer therapy), performing ...

Human cellular glutathione peroxidase 1 (hGPX1) is a selenium-dependent enzyme that participates in the detoxification of hydrogen peroxide and a wide range of organic peroxides. We conducted a case-control study nested within the alpha-Tocopherol, beta-Carotene Cancer Prevention Study cohort to evaluate the association between the proline to leucine polymorphism at codon 198 of hGPX1 and lung ...

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