There is increasing awareness of the link between impaired circadian clocks and multiple metabolic diseases. However, the impairment of the circadian clock by type 2 diabetes has not been fully elucidated. To understand whether and how the function of circadian clock is impaired under the diabetic condition, we examined not only the expression of circadian genes in the heart and pineal gland bu...

As part of the Phase III luminosity upgrade, the Cornell Electron-Positron Storage Ring (CESR) RF system has been upgraded from normal conducting (NRF) to superconducting (SRF) cavaties. The new superconducting cavities change the overall impedance of CESR and thus change the longitudinal bunch distribution. Measurements of the single bunch longitudinal distribution have been made using a strea...

Geraniin, a hydrolysable tannin, used in traditional medicine in Southeast Asia, is known to exhibit various biological activities. As an antioxidant it is known to up-regulate phase II enzyme Heme oxygenase-1 (HO-1). However its mechanism is not clearly understood. Nuclear factor erythroid-derived 2 related factor 2 (Nrf-2) is transcriptionally up-regulated by Extracellular signal-regulated ki...

Abstract Forkhead transcription factor (FoxO) plays key roles in the induction of various downstream genes involved inhibition cellular metabolism, cell death, cycle, and oxidative stress responses. FoxO6 is expressed liver, skeletal muscle, hippocampus brain. also has been proposed to play a role promotion insulin resistance, inflammation. In this study, we tried determine neuroinflammation in...

The competition graph of a digraph D is defined as a graph which has the same vertex set as D and has an edge xy between two distinct vertices x and y if and only if, for some vertex z ∈ V (D), the arcs (x, z) and (y, z) are in D. The competition number of a graph G is defined to be the smallest number k such that G together with k isolated vertices is the competition graph of an acyclic digrap...