The purpose of the study was to investigate determinants of acute mountain sickness after rapid ascent to high altitude. A total of 21 climbers were studied ascending from <1,200 m to Capanna Regina Margherita, a hut in the Alps at 4,559 m, within <24 h. During their overnight stay at 4,559 m, breathing patterns and ventilation were recorded by calibrated respiratory inductive plethysmography a...

The key elements in acclimatization aim at securing the oxygen supply to tissues and organs of the body with an optimal oxygen tension of the arterial blood. In acute exposure, ventilation and heart rate are elevated with a minimum reduction in stroke volume. In addition, plasma volume is reduced over 24-48 h to improve the oxygen-carrying capacity of the blood, and is further improved during a...

1. To investigate the mechanisms of acute mountain sickness, 22 subjects travelled to 3100 m by road and the following day walked to 4300 m on Mount Kenya. Control measurements were made over 2 days at 1300 m before ascent and for 2 days after arrival at 4300 m. These included body weight, 24 h urine volume, 24 h sodium and potassium excretion, blood haemoglobin, packed cell volume, and symptom...

Abstract. There have been rapid increases in both the number and expansion of proglacial lakes across High Mountain Asia. However, relationship between glacier dynamics remains unclear Himalayan region. Here we present surface elevation, flow-velocity changes, lake Thorthormi Lugge glaciers Lunana region, Bhutanese Himalaya, during 2000–2018 period using photogrammetry GPS survey data. The lowe...

Damavand volcano is located 60 km to the East North- East of Tehran. It is a dormant stratovolcano outcrop in the Alborz Mountains of northern Iran and is the highest mountain (5670 m) in the Middle East and West Asia. Mazandaran Province, one of the most populous provinces by population density, Semnan and Gorgan provinces further east are neighbours of the Damavand. Volcanism in Damavand goes...

BACKGROUND AND PURPOSE Arterial spin labeling (ASL) is a perfusion imaging technique that does not require gadolinium. The study aimed to assess the reliability of ASL for evaluating reperfusion in acute ischemic stroke in comparison with dynamic susceptibility contrast (DSC) imaging. METHODS The study included 24 patients with acute ischemic stroke on admission and 24-hour follow-up ASL and ...

BACKGROUND Aflatoxin B1 (AFB1) is a highly toxic and hepatocarcinogenic metabolite produced by Aspergillus species. Some natural products are known to kill fungi and destroy toxins and toxin-producing agents. OBJECTIVES The purpose of this study is to provide experimental data on the antifungal activity of cumin oils and their components that could be considered suitable for application in fo...