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BACKGROUND Whole blood (WB) has been used in combat since World War I as it is readily available and replaces every element of shed blood. Component therapy has become standard; however, recent military successes with WB resuscitation have revived the debate regarding wider WB use. Characterization of optimal WB storage is needed. We hypothesized that refrigeration preserves WB function and tha...
BACKGROUND/AIMS Cardiac fibrosis after myocardial infarction (MI) has been identified as a key factor in the development of heart failure, but the mechanisms undelying cardiac fibrosis remained unknown. microRNAs (miRNAs) are novel mechanisms leading to fibrotic diseases, including cardiac fibrosis. Previous studies revealed that miR-22 might be a potential target. However, the roles and mechan...
This paper considers the maximum value of the permanent over the class H(m, n) of n × n Hessenberg, (0, 1)-matrices with m 1’s, and shows that among those matrices that attain the maximum value there exists a matrix with a special form. This special form determines the exact value of the maximum permanent on H(m, n) for certain values of m and n.
This final overview draws on the papers selected for this volume and other sources to identify obstacles to sexual behaviour change in the African AIDS epidemic. Limitations to existing interventions and possible new interventions are then discussed. Obstacles to behavioural change are identified as the adherence to the present sexual culture; the refusal of leaders to recognize or come to term...
The sets generated as the long time attractors of “physical” dynamical systems described by ordinary differential equations or discrete evolution equations in the case of maps such as the Hénon map appear to be very complicated, often with unpleasant properties such as the lack of robustness (the parameters leading to chaotic and nonchaotic solution may be intertwined on an arbitrarily small sc...
Computi ng is the science of information processing, and the generation and manipulation of information pervades all aspects of computing. Nevertheless, we feel confident in asserting that information—data and knowledge—is even more important in the Grid environment than in other domains. We make this assertion for two reasons. First, the virtual organizations that define Grid systems are forme...
Q: How long w i l l i t be before this rou nd o f dow nsiz ing is completed? A: What you arc seeing now is the be g inn ing 'o f the second wave o f downsizing, w h ich really was formalized by the revo lt in Iran. We already had started on the downsiz ing. The j cars had already been en gineered. We increased the capacity o f those cars — we changed all the plans at that point. W e'll start ...
Single heavy atoms supported on thin carbon film were first imaged by Crewe, Wall and Langmore with their dark-field STEM. This glimpse into a hitherto invisible world we owe undeniably to Crewe's vision and determination, and to his gift to electrify, engage and encourage talented students. Since this successful event happened during my sabbatical stay in Crewe's group, the editors of this mem...
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