نتایج جستجو برای: 3 kinase

تعداد نتایج: 1981504  

Journal: :Journal of Cancer Therapy 2021

The original online version of this article (Guo, R., Wang, X., Zhang, R., Shi, H., Qiao, Y., Yun, W., Ge, Lin, Y. and Lei, J. (2015) Response Subcutaneous Xenografts of Endometrial Cancer in Nude Mice to Inhibitors Phosphatidylinositol 3-Kinase/Akt Mitogen-Activated Protein Kinase (MAPK) Pathways: An Effective Therapeutic Strategy for Endometrial Cancer. Journal Therapy, 6, 1083-1092. htt...

2003
Angel Ciprés Silvia Carrasco Ernesto Merino John R. Falck Isabel Mérida

Diacylglycerol kinase (DAGK ), like all type I DAGKs, has calcium regulatory motifs that act as negative regulators of enzyme activity and localization. Accordingly, DAGK is activated by phospholipase C-coupled receptors in a calcium-dependent manner. One of the first functions attributed to DAGK in lymphocytes was that of regulating interleukin 2-induced cell cycle entry. Interleukin-2 nonethe...

Journal: :Biochemical Society transactions 2004
L C Foukas P R Shepherd

Class I phosphoinositide 3-kinases were originally characterized as lipid kinases, although more than 10 years ago they were also found to phosphorylate protein serine residues. However, while there is a vast amount of data on the function of this lipid kinase activity, relatively little is known about the function of the protein kinase activity. We discuss the evidence that suggests that the p...

Journal: :Indian Journal of Pharmaceutical Sciences 2022

Accumulation of amyloid beta and its toxicity are the common features in Alzheimer’s disease. Autophagy plays an important role development progression disease by causing selfdegradation accumulated from neurons. Glycitin has been found as major phytochemical constituent soybean, which shows neuroprotective function The present study aims to explore glycitin clearance reducing neuronal cells. h...

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