Strength of both muscles and bone are important for fracture prevention in osteoporotic individuals. Therefore, drugs that are preclinically tested in animals for preventing or treating osteoporosis, and reducing fracture risk, should not only be checked for their effects on bone strength, but also for those on muscle strength. We developed a rat model to measure both in the same animal, using ...

This paper presents a numerical investigation and statistical analysis of laser bending of Titanium sheets. The aim of the present simulation is to identify the response through response surface methodology related to bending angle and characterize the effects of input parameters: laser power, spot diameter, scanning speed and plate thickness. The numerical simulations are carried out based on ...

DNA bending plays an important role in many biological processes, but its molecular and energetic details as a function of base sequence remain to be fully understood. Using a recently developed restraint, we have studied the controlled bending of four different B-DNA oligomers using molecular dynamics simulations. Umbrella sampling with the AMBER program and the recent parmbsc0 force field yie...

This paper derives expressions for the arc length and the bending energy of quadratic Bézier curves. The formulae are in terms of the control point coordinates. For fixed start and end points of the Bézier curve, the locus of the middle control point is analyzed for curves of fixed arc length or bending energy. In the case of arc length this locus is convex. For bending energy it is not. Given ...

Objectives. The objective was to determine the fracture and cyclic fatigue properties of composite–dentin beams bonded with a self-etching adhesive in four-point bend. Methods. Beams of rectangular cross-section were shaped to a size of ∼0.87mm×0.87mm×10mm and placed in a four-point bending apparatus, with the loading points 1.8 and 7.2mm apart, with the interface centered between the inner rol...

To elucidate the mechanism of oscillatory bending in cilia and flagella, we studied the effect of protease digestion on the response of axonemes to localized application of ATP. When the axonemes were treated with elastase and then reactivated locally by ATP iontophoresis, a pair of local bends were formed due to localized unidirectional sliding in the vicinity of the ATP pipette. Upon repeated...

For better protection, good toughness and robust flexibility, all life plants have skin tissue, likewise, books covers. In this paper, interlayer friction is considered as perturbation, hardcover book-like laminates with internal are studied. quasi-static problems, the bending response energy dissipation of three-point support plate analyzed in detail. Our numerical studies show that cover a bo...

Piezotronics is a new field integrating piezoelectric effect into nanoelectronics, which has attracted much attention for the fundamental research and potential applications. In this paper, the piezotronic effect of zinc oxide (ZnO) nanowires, including the response of the electrical transport and photoconducting behaviors on the nanowire bending, has been investigated by in situ transmission e...

This paper derives expressions for the arc length and the bending energy of quadratic Bézier curves. The formulae are in terms of the control point coordinates. For fixed start and end points of the Bézier curve, the locus of the middle control point is analyzed for curves of fixed arc length or bending energy. In the case of arc length this locus is convex. For bending energy it is not. Given ...

This study measured the bending stiffness of the spine when it is subjected to posteroanterior mobilization force. The lumbar spine was modeled as an initially curved beam column supported over the rib cage and the pelvis. Posteroanterior mobilization was assumed to be three-point bending of the beam. The mobilization force was measured by the mounting of a force plate onto the manipulation cou...