The content of n-3 (omega 3) polyunsaturated fatty acids in fat tissue is an indicator of their long-term consumption. Therefore, a method for determining n-3 fatty acids in human fat tissue microbiopsies was validated and the stability of n-3 fatty acids in biopsies was checked under various conditions of storage. Methyl esters were prepared from 25 to 35 mg adipose tissue and separated by cap...

Background A recent publication on the topic of normal weight obesity [1] has received media attention. The investigators used the National Health and Nutrition Examination Survey database, containing information on body mass index (BMI), percent body fat and metabolic problems related to obesity from over 13,000 adults age 20-80. Using the traditional BMI cutoff values of 25 kg/m for normal w...

Within the context of reduced-fat diets, the effects of incorporating a fat high in stearic acid and adding moderate amounts of dietary cholesterol were examined in 14 middle-aged and elderly women and men (range, 46 to 78 years) with low-density lipoprotein cholesterol (LDL-C) concentrations > 130 mg/dL (range, 133 to 219 mg/dL) at screening. The subjects consumed each of the five diets, which...

BACKGROUND Chronic hypertension leads to cardiac hypertrophy, heart failure, and premature death. Little is known about the impact of dietary macronutrient composition on hypertension-induced cardiac hypertrophy and mortality. We investigated the effects of consuming either a high complex carbohydrate diet, a high simple sugar diet, or a high fat diet on cardiac hypertrophy and mortality in hyp...

This investigation evaluated the relationship between smoking status and body fatness, dietary intake, and physical activity in adults. Subjects were 210 males who were either regular cigarette smokers (n = 35) or nonsmokers (n = 175). Estimated body fat and waist-to-hip (girth) measurements were carefully obtained. Additionally, a sensitive assessment of long-term dietary intake and a multifac...

Introduction ‘Count genes, not calories’ was the title of a nutrition article in the Financial Times of Friday, 13 June 2003. It referred to the results of the Human Genome Project and the discovery of our 35 000 genes, whose functions are currently both known and unknown. It also mentioned the study that painstakingly and systematically analysed all 17 000 genes of the Caenorhabditis elegans w...

The effects of an increasing proportion of crushed linseed (CL) in combination with varying forage type (grass or corn silage) and forage to concentrate ratio (F:C), and their interactions on milk fatty acid (FA) profile of high-producing dairy cows was studied using a 3-factor Box-Behnken design. Sixteen Holstein and 20 Swedish Red cows were blocked according to breed, parity, and milk yield, ...

BACKGROUND Previous studies indicate that the administration of melatonin caused body weight and abdominal visceral fat reductions in rodent models of hyperadiposity. The objective of the present study performed in high-fat fed rats was to evaluate the activity of melatonin on gene expression of some medial basal hypothalamus (MBH) signals involved in feeding behavior regulation, including neur...

The role of carbohydrates on mood and cognition is fairly well established, however research examining the behavioural effects of the other macronutrients is limited. The current study compared the effects of a 25 g glucose drink to energetically matched protein and fat drinks and an inert placebo. Following a blind, placebo-controlled, randomised crossover design, 18 healthy young adults consu...

OBJECTIVE To assess body size perception among African American women using cultural definitions of body size terms. METHODS Sixty-nine African American women classified Body Image Scale figures as overweight, obese, and too fat, and independently selected the figure they considered closest to their current body size. RESULTS Body size classifications of figures did not vary by participant ...