Exogenous sphingosine-1-phosphate (S1P), a lipid mediator in blood, attenuates acute microvascular permeability increases via receptor S1P1 to stabilize the endothelium. To evaluate the contribution of erythrocytes as an endogenous source of S1P to the regulation of basal permeability, we measured permeability coefficients in intact individually perfused venular microvessels of rat mesentery. T...

Abstract In this study, the hot tensile test was carried out using extruded and annealed Mg-1Al-6Y alloy. The effect of temperature strain rate on deformation behavior alloy systematically studied at different temperatures (200 °C ∼ 350 °C) rates (8 × 10 −5 s −1 1.6 −3 ). addition, evolution microstructure when is investigated. results showed that as increased or decreased, peak stress decrease...

Coffin, Benoit, Sophie Fossati, Bernard Flourié, Marc Lémann, Pauline Jouet, Claire Franchisseur, Raymond Jian, and Jean-Claude Rambaud. Regional effects of cholecystokinin octapeptide on colonic phasic and tonic motility in healthy humans. Am. J. Physiol. 276 (Gastrointest. Liver Physiol. 39): G767–G772, 1999.—The aim of this study was to assess in nine healthy subjects the effects of CCK octa...

We determined the effects of voluntary wheel running on the hypothalamic-pituitary-adrenal (HPA) axis, and the peripheral determinants of glucocorticoids action, in male Zucker diabetic fatty (ZDF) rats. Six-week-old euglycemic ZDF rats were divided into Basal, Sedentary, and Exercise groups (n = 8-9 per group). Basal animals were immediately killed, whereas Sedentary and Exercising rats were m...

Onions are an important vegetable crop, which is infected by many soils and foliar pathogens. Among them, Fusarium Basal Rot (FBR) causes yield losses of up to 50 per cent in the field 30 40 during post-harvest storage bulbs. For management basal rot onion, efficacy native antagonists such as six different Trichoderma sp. (T1-T6), five Bacillus (B1-B5) oil cakes was assessed against oxysporum f...

this study investigated the effects of the dietary supplementation of zizyphus mauritianaleaf meal (zlm) on the performance of yankasa lambs. twenty five lambs aged between 6 and 8 months were randomly divided into five groups of five animals each in a completely randomized design to receive supplementary diets containing 0, 10, 20, 30 and 40% zlm as replacement for cotton seed cake in concentr...

Epidermal growth factor receptors play an important role in airway epithelial cell growth and differentiation. The current study investigates the expression profiles of EGF, EGFR and ERBB4 in patients with nasal polyps (NP), and their response to glucocorticosteroid (GC) treatment. Fifty patients with NP (40 without GC treatment and 10 with oral GC) and 20 control subjects with septal deviation...

The aim of this study was to assess in nine healthy subjects the effects of CCK octapeptide (CCK-8) on colonic tonic activity, measured by a barostat, and phasic activity, measured by manometry. On 2 consecutive days, recordings were performed in the unprepared proximal and distal colons during intravenous infusion of saline and CCK-8 at 5, 20, and 40 ng ⋅ kg-1 ⋅ h-1. In the proximal colon CCK-...