DOI: 10.1002/adtp.202100050 Adv. Therap. 2021, 4, 2100050 The authors are correcting this article because they accidentally included a mistake in figure 4B and 6. These errors do not affect the results or conclusions of paper. sincerely apologize for any confusion may have caused. In Figure 4b fluorescent image green living cell stain was wrongly used during assembly 4. correct is as follow: 6b...

serovars of lisreria l1iollocyrogelles were determined. sera of aborted samples (200) were collected from different hospitals in tehran and were tested serologically by immunofluorescent antibody methods (if tests). 137 positive sera were identified. positive sera were tested against 12 serovars of listeria l1iollocytogelles separately. titers of antibody in patients' sera for all serovars...

Quatro saponinas esteroidais e três sapogeninas foram identificadas das partes aéreas de Brachiaria decumbens. As estruturas desses compostos foram estabelecidas através de métodos químicos e espectroscópicos (RMN de H e C, HMBC, HMQC) como 3 -metóxi-lanost-9(11)-eno (1), diosgenina (2a), iamogenina (2b), 3-O-D-glicopiranosil-24(S)-etil-22E-deidrocolesterol (3a), 3O-D-glicopiranosil-24(R)-etil-...

Here we report the synthesis, pharmacological and pharmacokinetic evaluation of a pilot set of compounds structurally related to the potent and selective 5-HT7 ligand LP-211. Among the studied compounds, N-pyridin-3-ylmethyl-3-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]ethoxy]propanamide (4b) showed high affinity for 5-HT7 receptors (K(i)=23.8 nM), selectivity over 5-HT1A receptors (>50-fold)...

With normal intonation, (4a) is ungrammatical and (4b) is unambiguous with the adverbial around midnight construed only with the matrix clause. However, Ross (1986: 180–181) states that ‘[i]f the preposed adverbials bear heavy stress, [...,] [(4a)] becomes grammatical, and [(4b)] becomes ambiguous, for the adverbial can modify the lower verb as well as the main verb’. If Ross’ observation is co...

A new series of 6 dimeric trioxane sulfones has been prepared from the natural trioxane artemisinin in five or six chemical steps. One of these thermally and hydrolytically stable new chemical entities (4c) completely cured malaria-infected mice via a single oral dose of 144 mg/kg. At a much lower single oral dose of only 54 mg/kg combined with 13 mg/kg of mefloquine hydrochloride, this trioxan...

Molecular serogroup-related PCR typing has made the determination of serotypes of Listeria monocytogenes isolates easy and rapid. Amplification of selected lineage- and serotype-related genes can produce serotype patterns reflecting the four major serotypes, 1/2a, 1/2b, 1/2c, and 4b. We found that four isolates in our routine testing had a pattern with the four bands lmo0737, ORF2110, ORF2819, ...

In the development of oligoarginine-based prodrugs with self-cleavable spacers for intestinal absorption, we previously reported a series of spacers with variable half-lives of parent compound release based on a neighboring group participation mechanism from an amino acid side-chain structure next to the succinyl moiety. In the present study, to diversify the half-life of the spacer, we first s...

Glycosylation is a common post-translational modification of proteins implicated in cellular recognition processes and controlling protein conformation.1 Typically, carbohydrates are O-linked to serine (Ser) and threonine (Thr) or N-linked to asparagine (Asn). Glycosylation of (2S,4R)-4-hydroxyproline (Hyp) is widespread in the plant kingdom and occurs in Hyp-rich glycoproteins (HRGPs) that are...

Recently we reported that removal of noncovalently bonded protein from glutenin resulted in decreased viscoelasticity. In that study, two glutenin fractions were isolated by successive gel filtration of glutenin on Sephadex G-200 in the solvents acetic acid-guanidine hydrochloride (GuHCl)-cetyltrimethylammonium bromide (AGC) and sodium dodecyl sulfate (SDS). This note reports the S20,W values o...