This research aims to evaluate the wound healing effect of noni’s leaf extract (Morinda citrifolia L.) based on phytochemical analysis, number fibroblast cells, diameter, time, TNF-a and IL-1 at inflammation stage, PDGF TGF-b proliferation stage. study is a true experimental with post-test-only control group design. We divided 25 male Wistar rats into five groups; positive (with povidone-iodine...

ABSTRACT. The chemical constituents of the methanolic extract Emex spinosa shoots were primarily characterized by gas-chromatography-mass spectrometry analysis (GC-MS), forty components identified. major ethyl 2-hydroxycyclohexane-1-carboxylate (10.11%), 3,5-dihydroxy-6-methyl-2,3-dihydro-4H-pyran-4-one (38.09%), 2-propyltetrahydro-2H-pyran-3-ol (5.75%), oleic acid (8.02%), and methyl (E)-octad...

(E)-5-(Methoxyimino)-1,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one was prepared by a condensation reaction from 3,4-dihydro-1H-benzo[b]azepin-2,5-dione and O-methylhydroxylamine. The configuration at the C=N double bond determined X-ray crystallography.

With 3,3'-bi[benzo[b]thiophenyl] as starting material, dibenzo[d,d']benzo[1,2-b:4,3-b']dithiophene, a [5]heterohelicene, was synthesized efficiently in 60% yield via formylation and McMurry reaction. Cyclopenta[1,2-b:4,3-b']bis(benzo[d]thiophen)-6-one, another interesting helical ketone, was also prepared in 79% yield via deprotonation and ketonization of 3,3'-bi[benzo[b]thiophenyl]. In additio...

In the title compound, C15H13NOS, the thia-zine ring adopts a twisted boat conformation and the dihedral angle between the aromatic rings is 86.54 (4)°. In the crystal, mol-ecules are linked by weak C-H⋯O inter-actions, resulting in chains along [010].

In the title compound, C16H13NOS, the 1,4-thia-zine ring displays a screw-boat conformation. The conformation about the ethene bond [1.344 (2) Å] is Z. The plane of the fused benzene ring makes a dihedral angle of 58.95 (9)° with the pendent phenyl ring, indicating a twisted conformation in the mol-ecule. In the crystal, mol-ecules are linked by pairs of C-H⋯O hydrogen bonds, forming inversion ...

Doping of heteroatoms such as nitrogen into the lattice structure of graphene can tune and tailor the overall electronic properties. N-doped graphene, depending on the nitrogen bonding mode and/or bonding configuration, displays subtly altered properties in comparison to pristine graphene. However, there remains a disappointing shortage of reliable methods for introducing dopants in a controlle...

The convenient and multigram synthesis of a linear benzo[b]dithiophene (BDT) structure is proposed (dimethyl 3,7-diamino-4,8-bis((2-methoxy-2-oxoethyl)thio)benzo[1,2-b:4,5-b’]dithiophene-2,6-dicarboxylate). starting materials are commercially available 2,3,5,6-tetrachloroterephthalonitrile methyl 2-mercaptoacetate, which undergo aromatic substitution, followed by cyclization reaction in basic c...