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In a study of the protein composition of lymphoid tissue, Roberts and White1 in 1949 reported that a fraction isolated from calf thymus produced thymic hypertrophy when injected for a ten-day period into adult rats. Since this suggestion of a humoral role for the thymus in stimulating lymphocytopoiesis, considerable additional evidence'has appeared. This effect appears to have some relation to ...
Amorphophallus paeoniifolius known as Elephant foot yam is a highly potential tropical tuber crop of Areace family. The tubers are rich in nutrients. It is a healthy low-fat food containing a good source of protein as well as starch. It is a natural product that is high in fiber, rich in potassium, calcium (50 mg g-1), phosphorus (34 mg g-1) vitamin A (260 IU g-1), vitamin B6, as well as with t...
There is increasing evidence that free radical damage may be an important cause of some of the adverse effects of disease and advancing age. Much of the clinical evidence to support this hypothesis is based on the protective effect sometimes observed in those on diets high in antioxidants and those given antioxidants therapeutically. Further support would be obtained if plasma markers for oxida...
The D2 dopamine receptor is a member of the family of Gprotein linked receptors. They are thought to consist of seven hydrophobic transmembrane domains (TMD) linked together by intraand extra-cellular loops. Within this group of receptors there is a high degree of homology, particularly within the membrane spanning regions [ 11, and within these domains certain conserved amino acids have been i...
Previous work in this laboratory [ 1.2.31 showed that elevation of cyclic AMP has dual effects (A and B below) on the expression of the LDL receptor in human vascular smooth muscle cells (VSMC) and skin fibroblasts. A). Cyclic AMP elevating agents stimulate LDL receptor activity [ I ] in human cells by increasing the rate of receptor protein synthesis [2]. The stimulation is not secondary to th...
There is increasing evidence that conversion of angiotensin I into angiotensin I1 can occur in the renal vasculature of humans [l l , and in the vascular beds of the hind limb of the dog 121. In previous experiments the specific angiotensionconverting enzyme in rat aorta [31 has been demonstrated. More recently, Mizuno et al. [41 have studied the subcellular localization of the enzyme activity ...
INTRODUCTION. Human cartilage glycoprotein 39 (HC gp-39), a member of the mammalian protein family related in sequence to the bacterial chitinases, has been reported as a major secretory glycoprotein of cultured human articular chondrocytes and synovial fibroblasts [1]. Although HC gp39 was undetectable in normal cartilage by Northern and Western blot analyses, it was reported to be highly expr...
Calcium phosphate ceramics are widely used as bone substitutes since they are biocompatible and bioactive. Having a chemical composition close to natural bone, calcium phosphate ceramics are promising bone substitute materials in orthopaedics, maxillofacial surgery and dentistry. Hydroxyapatite (HA) and tricalcium phosphate (TCP) are the most commonly used calcium phosphates, because their calc...
Some HVAC systems save energy by creating stratified air temperature distributions in which the occupied lower regions are cooler and the upper regions warmer. Comfort standards prescribe a 3°C limit to vertical stratification, independent of where the mean temperature is relative to the comfort zone. This paper evaluates thermal comfort in stratified environments using a model developed to pre...
Introduction Until recently, chronic nerve compression (CNC) injuries have been relatively understudied. Recent studies have shown that CNC injury induces Schwann cell proliferation and apoptosis with no morphologic evidence of axonal injury (1,2). It has also been shown that the axon undergoes a sprouting response within the zone of compression that is readily apparent by two weeks following i...
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